正念认知疗法联合个体化药物改善抑郁症伴躯体疼痛患者及其社会功能的临床研究

Clinical study of mindfulness cognitive therapy combined with individualized medicine in improving physical pain and their social function of patients with depression

目的分析正念认知疗法联合个体化药物改善抑郁症伴躯体疼痛患者的临床症状及其社会功能的临床效果。方法选取2019年6月-2021年12月在本院临床心理科门诊及住院诊治抑郁症伴躯体疼痛患者76例,根据随机表法分为2组,对照组给予口服氟哌噻吨美利曲辛片与盐酸度洛西汀的疗法。研究组在对照组的基础上联合正念认知疗法记录并比较两组在治疗前后的抑郁状态、正念水平、疼痛程度、社会功能、生活质量及每日平均抗抑郁药物剂量情况。结果治疗3个月后,两组患者五因素正念问卷(FFMQ)评分5个因子、SF-36评分5项指标水平、VAS与SDSS评分及总分均提高(P<0.05),但是研究组患者中重度组、轻度组的FFMQ评分5个因子、SF-36评分5项指标水平、VAS与SDSS评分及总分分别高于对照组中重度组、轻度组(P<0.05)。结论正念认知疗法联合个体化药物可以有效地减轻抑郁症伴躯体疼痛患者的抑郁状态与疼痛程度,提高社会功能与生活质量,具有较高的临床价值。

Objective To analyze the clinical effect of mindfulness cognitive therapy combined with individualized medicine on improving the clinical symptoms and social function of patients with depression and somatic pain.Methods A total of 76 patients with depression and body pain were selected from department of clinical psychology in our hospital from June 2019 to December 2021.They were divided into 2 groups according to random table method.The control group was given oral flupentixol melitrixen tablets and duloxetine hydrochloride therapy.The study group were treated with cognitive therapy on the basis of the control group.The depression status,mindfulness level,pain level,social function,quality of life and average daily antidepressant dose of the two groups before and after treatment were recorded and compared.Results After 3 months of treatment,five factors of 5-factor mindfulness questionnaire(FFMQ)score,five indexes of SF-36 score,VAS and SDSS score and total score were increased in two groups(P<0.05).However,five factors of FFMQ score,five indexes of SF-36 score,VAS and SDSS score and total score in moderate to severe group and mild group in study group were higher than those of control group(P<0.05).Conclusion Mindfulness cognitive therapy combined with individualized medicine can effectively reduce the depressive state and pain degree of patients with depression and physical pain,improve social function and quality of life,and it has high clinical value.