温针灸联合常规疗法治疗小儿消化不良性腹泻的效果及对胃肠激素的调节作用分析

Analysis of the effect of warm acupuncture and moxibustion combined with conventional therapy on children's dyspeptic diarrhea and the regulation of gastrointestinal hormones

目的:研究温针灸联合常规疗法治疗小儿消化不良性腹泻的效果及对胃肠激素的调节作用。方法:选取我院2021年8月—2023年4月收治的82例消化不良性腹泻患儿作为研究对象,采用随机信封法分为对照组(41例)、研究组(41例),对照组予以常规疗法,研究组在此基础上予以温针灸治疗。比较两组临床疗效、临床症状消失时间(腹痛、腹泻、腹胀)、胃肠激素[胃动素(MTL)、胃泌素(GAS)、血管活性肠肽(VIP)、生长抑素(SS)]、胃动力[胃收缩频率(F)、胃收缩幅度(P)、胃排空率、运动指数(MI)]及不良反应。结果:研究组总有效率97.56%(40/41),高于对照组的80.49%(33/41)(P<0.05);研究组腹痛、腹泻、腹胀消失时间较对照组缩短(P<0.05);治疗后研究组SS水平较对照组均升高,MTL、GAS、VIP水平较对照组均降低(P<0.05);治疗后研究组F、P、胃排空率及MI较对照组均升高(P<0.05);研究组不良反应总发生率7.32%(3/41)与对照组4.88%(2/41)比较,差异无统计学意义(P>0.05)。结论:温针灸联合常规疗法能有效改善消化不良性腹泻患儿临床症状,调节胃肠激素与胃动力,治疗效果显著,且安全性较高。

Objective:To study the effect of warm acupuncture and moxibustion combined with conventional therapy on children with dyspeptic diarrhea and the regulation of gastrointestinal hormones.Methods:A total of 82 children with dyspeptic diarrhea admitted to our hospital from August 2021 to April 2023 were selected as the study objects,and were divided into control group(41 cases)and study group(41 cases)by random envelope method.The control group was given conventional treatment,and the study group was given warm acupuncture treatment on this basis.The clinical efficacy,duration of clinical symptoms(abdominal pain,diarrhea,abdominal distension),gastrointestinal hormones[MTL,gastrin(GAS),vasoactive intestinal peptide(VIP),somatostatin(SS)],gastric motility[frequency of gastric contraction(F),amplitude of gastric contraction(P),gastric emptying rate,motor index(MI)]and adverse reactions were compared between the two groups.Results:The total effective rate of the study group was 97.56%,which was higher than 80.49%of the control group(P<0.05).The disappearance time of abdominal pain,diarrhea and distension in the study group was shorter than that in the control group(P<0.05).After treatment,the SS level of the study group was higher than that of the control group,and the MTL,GAS and VIP levels were lower than that of the control group(P<0.05).After treatment,the rates of F,P,gastric emptying and MI in the study group were higher than those in the control group(P<0.05).The total incidence of adverse reactions in the study group was 7.32%(3/41)compared with 4.88%(2/41)in the control group(P>0.05).Conclusion:Warm acupuncture and moxibustion combined with conventional therapy can effectively improve the clinical symptoms of children with dyspeptic diarrhea,regulate gastrointestinal hormones and gastric motility,the therapeutic effect is significant,and the safety is high.