社会归属在不孕症女性抑郁状态与生育生活质量关联中的中介作用

Mediating role of social belonging in the association between depression and fertility quality of life in infertile women

目的探讨不孕女性抑郁状态、社会归属及生育生活质量之间的关系,为有效改善不孕女性生活质量措施的制定提供理论依据。方法2022年7月至2022年10月期间随机抽样选取安徽医科大学附属第一医院的生殖辅助中心不孕症女性治疗患者400例,采用一般基础问卷,抑郁筛查自评量表(PHQ-9)、社会归属测量问卷及生育生活质量量表进行调查。采用Spearman相关分析各变量间的关联,通过Bootstrap程序和PROCESS软件检验中介效应。结果400例不孕女性抑郁得分中位数为5分,达到亚临床轻度抑郁水平,社会归属测量得分中位数为12分,生育生活质量得分中位数62.87分。社会归属与抑郁状态呈负相关(r=-0.206,P<0.001);社会归属与生育生活质量呈正相关(r=0.267,P<0.001);抑郁状态与生育生活质量呈负相关(r=-0.428,P<0.001)。中介分析显示,在控制相关变量后,不孕症女性抑郁状态对生育生活质量的间接效应为-0.0690(95%CI:-0.1733~-0.0083),直接效应为-1.0191(95%CI:-1.4363~-0.6018),通过社会归属对不孕症女性抑郁状态的生育生活质量中介效应占总效应的6.34%。结论社会归属在不孕症女性抑郁状态和生育生活质量中起部分中介作用。应及时关注不孕症女性心理情况,给予她们更多的社会认可和支持以改善生育生活质量。

Objective To explore the relationship among depression,social belonging and fertility quality of life of infertile women,and to provide a theoretical basis for the development of effective measures to improve the quality of life of infertile women.Methods From July 2022 to October 2022,a random sample of 400 patients treated for infertility in the Reproductive Assisting Centre of the First Hospital of Anhui Medical University were selected using a general basic questionnaire,the Depression Screening Self-Rating Scale(PHQ-9),the Social Attribution Measurement Questionnaire and the Fertility Quality of Life Scale quality of life questionnaire(FertiQoL)were administered.Spearman correlation was used to analyze the association between the variables,and mediating effects were examined by Bootstrap procedure and PROCESS software.Results The 400 infertile women had a median depression score of 5,reaching a subclinical mild level of depression,a median score of 12 on the social belonging measure,and a median score of 62.87 on the FertiQoL.Social belonging was negatively correlated with depression(r=-0.206,P<0.001);social belonging was positively correlated with FertiQoL(r=0.267,P<0.001);and depression was negatively correlated with FertiQoL(r=-0.428,P<0.001).Mediation analysis showed that after controlling for relevant variables,the indirect effect of depression on FertiQoL in infertile women was-0.0690(95%CI:-0.1733--0.0083),and the direct effect was-1.0191(95%CI:-1.4363--0.6018),the mediating effect of FertiQoL through social belonging on depression in infertile women accounted for 6.34%of the total effect.Conclusion Social belonging plays a partial mediating role in depression and FertiQoL among infertile women.Infertile women should be given timely attention to their psychological situation and given more social recognition and support to improve their FertiQoL.