中青年男性握力与颈动脉粥样硬化的关联研究

Correlation between grip strength and carotid atherosclerosis in young and middle-aged males

目的 探讨中青年男性握力水平和颈动脉粥样硬化的关联,为运动干预动脉粥样硬化的发生发展提供依据。方法 招募454名20~59岁男性,记录人体学指标,测量身体成分、握力、心肺耐力和相关血液指标并进行颈动脉超声检查。采用t检验、单因素方差分析、Logistic回归进行统计学分析。结果 相比于低握力水平组,高握力水平组的BMI低、RSMI大、心率低、TC低、HDL低、空腹血糖低、CIMT小、Crouse积分小、等级积分小,差异均有统计学意义(均P<0.05)。Logistic回归分析显示,调整BMI、RSMI、心率、TC、HDL、空腹血糖、VO_(2max)、收缩压、舒张压后,低水平和中等水平组发生颈动脉粥样硬化的风险高于高水平组(OR=2.79、1.71)。结论 较低握力的中青年男性存在动脉粥样硬化的风险较高,握力测量有助于评估动脉粥样硬化状况。

Objective To investigate the correlation between the level of grip strength and the occurrence of carotid atherosclerosis in middle-aged and young males,and to provide evidence for the intervention of exercise in the occurrence and development of atherosclerosis.Methods A total of 454 male participants aged 20-59 years were recruited for this study.Anthropometric measurements,body composition analysis,grip strength assessment,cardiorespiratory endurance testing,and relevant blood tests were conducted.Additionally,carotid artery ultrasound examination was performed.The collected data were analyzed using t-tests,One-way analysis of variance and logistic regression for statistical analysis.Results Compared to the low grip strength group,the high grip strength group showed statistically significant differences in BMI(lower),RSMI(higher),heart rate(lower),TC(lower),HDL(lower),fasting blood glucose(lower),CIMT(smaller),Crouse score(smaller),and grade score(smaller)(all P<0.05).Logistic regression analysis,adjusting for BMI,RSMI,heart rate,TC,HDL,fasting blood glucose,VO_(2max,) systolic blood pressure,and diastolic blood pressure,revealed that the low and moderate grip strength groups had a higher risk of carotid atherosclerosis compared to the high grip strength group(OR=2.79,1.71).Conclusions Low grip strength in young and middle-aged males is associated with a higher risk of atherosclerosis,and grip strength measurement can help to assess the status of atherosclerosis.