低剂量多层螺旋CT扫描与血清CA153及SCC检验对肺部炎性和癌性结节的鉴别

Differential Diagnosis of Pulmonary Inflammatory and Cancerous Nodules Using Low-Dose Multi-Slice Spiral CT Scanning and Serum CA153 and SCC Tests

目的:探析低剂量多层螺旋CT扫描与血清糖类抗原(CA153)、鳞状上皮细胞癌抗原(SCC)检验对肺部炎性和癌性结节鉴别的应用价值。方法:择取2021年1月~2023年1月本校直管和非直管附属医院收治的疑似肺癌患者100例,所有患者均接受低剂量多层螺旋CT、血清CA153以及SCC检查,以肺穿刺活检病理诊断结果为诊断金标准,分析低剂量多层螺旋CT扫描与血清CA153、SCC检验对肺炎性和癌性结节鉴别诊断中的应用价值。结果:低剂量多层螺旋CT扫描鉴别诊断肺癌患者准确度为89.00%,灵敏度为91.07%,特异度为86.36%;低剂量多层螺旋CT扫描与血清CA153、SCC检验对肺炎性结节、肺癌性结节诊断的AUC分别为0.887、0.845、0.843。结论:低剂量多层螺旋CT扫描鉴别诊断肺癌性结节、肺炎良性结节中的临床价值较高。

Objective:To explore the application value of low-dose multi-slice spiral CT scanning and serum carbohydrate antigen(CA153)and squamous cell carcinoma antigen(SCC)tests in distinguishing pulmonary inflammatory and cancerous nodules.Methods:100 suspected lung cancer patients admitted to our school’s direct and non direct affiliated hospitals from January 2021 to January 2023 were selected.All patients underwent low-dose multi-slice spiral CT,serum CA153,and SCC examinations.The diagnostic gold standard was the pathological results of lung biopsy.The application value of low-dose multi-slice spiral CT scanning,serum CA153,and SCC examinations in the differential diagnosis of pneumonia and cancerous nodules was analyzed.The results were confirmed by pathological examination of lung biopsy tissue.Results:The accuracy,sensitivity,and specificity of low-dose multi-slice spiral CT scanning in differential diagnosis of lung cancer patients were 89.00%,91.07%,and 86.36%,respectively.The results showed that low-dose multi-slice spiral CT scanning,serum CA153,and SCC tests had an AUC of 0.887,0.845,and 0.843 for the diagnosis of pneumonia and lung cancer nodules.Conclusion:Low dose multi-slice spiral CT scanning has high clinical value in differential diagnosis of lung cancer nodules and pneumonia benign nodules.