C反应蛋白联合降钙素原检测在长期住院精神疾病患者细菌性感染诊断中的应用价值

Application Value of C-Reactive Protein and Procalcitonin Detection in Diagnosis of Bacterial Infection in Long-Term Hospitalized Psychiatric Patients

目的:探讨C反应蛋白联合降钙素原检测在长期住院精神疾病患者细菌性感染诊断中的应用价值。方法:选取2021年6月—2023年12月于南通市紫琅医院长期住院并伴有细菌性感染的精神疾病患者96例作为研究组,另选取同期无细菌性感染的精神疾病患者96例作为对照组。检测两组C反应蛋白与降钙素原水平,分析C反应蛋白与降钙素原诊断细菌性感染的效能。结果:研究组C反应蛋白、降钙素原水平均高于对照组,差异有统计学意义(P<0.001)。C反应蛋白、降钙素原、C反应蛋白联合降钙素原诊断细菌性感染的受试者操作特征曲线下总面积分别为0.918、0.874、0.923,均具有良好的诊断价值,且联合检测诊断效能更高。结论:C反应蛋白联合降钙素原检测在长期住院精神疾病患者细菌性感染诊断中的应用价值较高,且联合检测能够提高诊断效能。

Objective:To explore the application value of C-reactive protein and procalcitonin detection in the diagnosis of bacterial infection in long-term hospitalized psychiatric patients.Methods:From June 2021 to December 2023,96 psychiatric patients who were long-term hospitalized in Nantong Zilang Hospital with bacterial infection were selected as the study group,and 96 psychiatric patients without bacterial infection during the same period were selected as the control group.The levels of C-reactive protein and procalcitonin in the two groups were detected.The diagnostic efficiency of C-reactive protein and procalcitonin for bacterial infection was analyzed.Results:The levels of C-reactive protein and procalcitonin in the study group were higher than those in the control group,and the difference was statistically significant(P<0.001).The total area under the receiver operating characteristic curve of C-reactive protein,procalcitonin,and C-reactive protein combined with procalcitonin in the diagnosis of bacterial infection were 0.918,0.874,and 0.923,respectively,indicating the good diagnostic value of three detection methods and higher diagnostic efficiency of the combined detection.Conclusion:The application value of C-reactive protein and procalcitonin detection in the diagnosis of bacterial infection in long-term hospitalized psychiatric patients is high,and the combined detection can improve the diagnostic efficiency.