新冠疫情防控下手足口病肠道病毒的流行特征及变迁趋势

Epidemic characteristics and changing trend of enterovirus infections in the context of prevention and control of COVID-19 epidemic

针对2019冠状病毒病(coronavirus disease 2019,COVID-19)疫情,在早期缺乏有效药物干预的情况下,大多数国家都采取了疫情防控措施,该措施的实施导致人们生活及行为方式的改变,减轻了COVID-19的传播.然而,这一策略对其他常见传染病的影响尚不清楚.本文通过分析疫情防控下手足口病肠道病毒的流行及变迁趋势,阐明实施疫情防控措施在减少手足口病肠道病毒流行方面非常有效,并对其基因变迁产生明显影响;探讨免疫力缺失和传染性疾病暴发之间的关系,提示疫情期间由于人们缺乏暴露于各种传染性病原体的机会导致免疫力缺失,未来可能出现多种传染病的共同流行,可为疫情大流行后常见及新发传染病的监测和防控、抗病毒药物和疫苗的研究提供启发.

In response to the coronavirus disease 2019(COVID-19)pandemic,most countries have implemented epidemic prevention and control measures in the early stages without effective drug intervention.The implementation of these measures has led to changes in people’s lifestyles and behaviors,reducing the spread of COVID-19.However,the impact of this strategy on other common infectious diseases is still unclear.This article analyzes the prevalence and changing trends of enteroviruse infections in the context of epidemic prevention and control,and clarifies that implementing epidemic prevention and control measures is very effective in reducing the prevalence of enteroviruse infections and has a significant impact on their genetic changes.By exploring the relationship between immune deficiency and outbreaks of infectious diseases,it is suggested that during the epidemic,the lack of exposure to various infectious pathogens may lead to immune deficiency,and there may be a common outbreak of multiple infectious diseases in the future.This finding can provide inspiration for the monitoring and prevention of common and emerging infectious diseases after the epidemic,as well as the research on antiviral drugs and vaccines.