参芪降糖胶囊对气阴两虚型2型糖尿病患者血糖波动的临床观察

Clinical Observation of Shenqi Jiangtang Capsule on Blood Glucose Fluctuation in Type 2 Diabetes Patients with Qi Yin Deficiency

目的:观察参芪降糖胶囊对气阴两虚型2型糖尿病患者血糖波动的临床疗效。方法:选取2022年7月1日—2023年6月30日我院住院治疗的64例气阴两虚型老年2型糖尿病患者作为研究对象,按照研究对象随机分为对照组和治疗组,对照组予以皮下注射胰岛素、口服降糖药常规降糖结合生活方式干预等综合治疗,治疗组在对照组综合干预的基础上予以参芪降糖胶囊治疗。观察两组治疗前后的中医证候症状积分量表、最大血糖波动幅度、血糖标准差、餐后血糖波动幅度、血脂常规,进行两组临床疗效对比分析。结果:治疗组总有效率为100.0%(32/32),显著优于对照组的90.6%(29/32),P<0.05。治疗后治疗组的中医证候症状评分、最大血糖波动幅度、血糖标准差、餐后血糖波动幅度、甘油三酯、总胆固醇、低密度脂蛋白胆固醇均低于治疗前且低于治疗后对照组,P<0.05。治疗后治疗组高密度脂蛋白胆固醇测定值均高于治疗前且高于治疗后对照组,P<0.05。结论:参芪降糖胶囊治疗气阴两虚型2型糖尿病临床疗效显著,可有效改善2型糖尿病患者相关症状,并可有效调节患者血糖波动及血脂水平,值得临床应用及进一步实验研究。

Objective:To observe the clinical efficacy of Shenqi Jiangtang Capsule on blood glucose fluctuations in patients with type 2 diabetes mellitus with Qi and Yin deficiency type.Methods:64 elderly type 2 diabetes patients with Qi and Yin deficiency who were hospitalized in our hospital from July 1,2022 to June 30,2023 were selected as the research subjects.They were randomly divided into a control group and a treatment group according to the research subjects.The control group The treatment group received comprehensive treatment such as subcutaneous insulin injection,oral hypoglycemic drugs,conventional hypoglycemic drugs,and lifestyle intervention,while the treatment group received Shenqi Jiangtang Capsules based on the comprehensive intervention of the control group.Observe the traditional Chinese medicine syndrome symptom score scale,maximum blood sugar fluctuation range,blood sugar standard deviation,postprandial blood sugar fluctuation range,and blood lipid routine of the two groups before and after treatment,and conduct a comparative analysis of the clinical efficacy of the two groups.Results:The total effective rate of the treatment group was 100.0%(32/32),which was significantly better than the 90.6%(29/32)of the control group(P<0.05).After treatment,the TCM syndrome symptom scores,maximum blood sugar fluctuation range,blood sugar standard deviation,postprandial blood sugar fluctuation range,triglycerides,total cholesterol,and low-density lipoprotein cholesterol in the treatment group were all lower than those before treatment and lower than those in the control group after treatment(P<0.05).After treatment,the measured values of high-density lipoprotein cholesterol in the treatment group were higher than those before treatment and higher than those in the control group after treatment(P<0.05).Conclusion:Shenqi Jiangtang Capsule has significant clinical efficacy in treating type 2 diabetes due to Qi and Yin deficiency.It can effectively improve the related symptoms of patients with type 2 diabetes,and can effectively regulate blood sugar fluctuations and blood lipid levels in patients.It is worthy of clinical application and further experimental research.