几种纳米氧化物杀菌能力的比较研究

A Comparative Study of Antibacterial Capability of Several Nano-oxides

纳米氧化物因具有优异的杀菌潜力广受瞩目,然而不同纳米氧化物的杀菌性能鲜有横向比较。该研究对纳米TiO2、纳米Al2O3、纳米MgO、纳米ZnO和纳米SiO25种常见纳米粒子的抗菌能力进行综合评估,测试菌株包括大肠杆菌、沙门氏菌、单核细胞增生李斯特菌和金黄色葡萄球菌。结果显示,纳米MgO表现出极强的杀菌效果,在1 mM浓度下,能有效杀死50%以上的细菌;而在5 mM浓度下,杀菌率高达90%以上。其次是纳米ZnO,对细菌也具有较强的杀菌作用。尤其对革兰氏阴性菌,纳米MgO和纳米ZnO的杀菌效果更为显著。纳米TiO2和纳米Al2O3虽然显示一定的杀菌潜力,但效果较弱。另外,SiO2纳米粒子未表现出任何杀菌能力。该研究对不同纳米氧化物的杀菌性能进行全面的比较分析,实验结果可为开发新型高效杀菌剂和抑菌材料提供有益的参考。

Nano-oxides have garnered significant attention due to their potential for antibacterial properties;however,there is a lack of comprehensive cross-comparison regarding the antibacterial performance of different nanoparticles.This study conducted a comprehensive evaluation of the antibacterial capabilities of five commonly used nanoparticles:nano-TiO2,nano-Al2O3,nano-MgO,nano-ZnO,and nano-SiO2.The test strains included Escherichia coli,Salmonella,Listeria monocytogenes,and Staphylococcus aureus.The results revealed that nano-MgO exhibited remarkably strong bactericidal effects.At a concentration of 1 mM,it effectively killed over 50%of the bacteria,and at a concentration of 5 mM,the bactericidal rate exceeded 90%.Nano-ZnO demonstrated the second most potent antibacterial action.Particularly against Gram-negative bacteria,nano-MgO and nano-ZnO showed more pronounced bactericidal effects.While nano-TiO2 and nano-Al2O3 exhibited some antibacterial potential,their effectiveness was relatively weak.Additionally,nano-SiO2 particles did not exhibit any antibacterial capability.These findings offer valuable references for the development of novel and efficient antibacterial agents and antimicrobial materials.