失笑散加味联合西医治疗结石性肾绞痛的临床效果

Clinical Effect of Shixiaosan Modified Combined With Western Medicine in the Treatment of Calculous Renal Colic

目的探讨失笑散加味联合西医治疗结石性肾绞痛的临床效果。方法选取2020年4月—2022年2月云南省大理白族自治州中医医院急诊科诊治的60例结石性肾绞痛患者为研究对象。根据治疗方案的不同均分2组,各30例。以常规西药治疗为对照组,观察组在对照组的基础上加用失笑散加味治疗。比较2组临床疗效、疼痛评分、结石清除率、结石排出时间和不良反应发生情况。结果观察组的总有效率为96.67%,高于对照组的80.00%,差异有统计学意义(P<0.05)。治疗后,观察组的疼痛评分为(1.54±0.23)分,低于对照组的(2.83±0.36)分,差异有统计学意义(P<0.05)。观察组结石清除率(90.00%)高于对照组(66.67%),观察组结石排出时间为(5.87±2.16)d,短于对照组的(8.49±2.83)d,差异有统计学意义(P<0.05)。2组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论失笑散加味联合西药治疗结石性肾绞痛可以缓解患者疼痛,促进结石排出,避免疼痛再发,且具有较好的安全性。

Objective The aim of this paper was to explore the clinical effect of Shixiaosan modified combined with western medicine in the treatment of calculous renal colic.Methods A total of 60 patients with calculous renal colic diagnosed and treated in the department of emergency,Dali Bai Autonomous Prefecture Chinese Medicine Hospital,Yunnan Province from April 2020 to February 2022 were entered into the study.According to the different treatment plan,they were divided into 2 groups with 30 cases each.The control group was treated with conventional western medicine,and the observation group was treated with Shixiaosan modified on the basis of the control group.The clinical efficacy,pain score,stone clearance rate,stone removal time and adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 96.67%,higher than that of the control group(80.00%),and the difference was statistically significant(P<0.05).After treatment,the pain score of the observation group was(1.54±0.23)points,which was lower than that of the control group(2.83±0.36)points,and the difference was statistically significant(P<0.05).The stone clearance rate of the observation group(90.00%)was higher than that of the control group(66.67%),and the stone expulsion time of the observation group was(5.87±2.16)d,which was shorter than that of the control group(8.49±2.83)d,the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion The combination of Shixiaosan modified with western medicine can relieve the pain of patients with calculous renal colic,promote the removal of stones,avoid the recurrence of pain,and has a good safety.