2014—2022年温州市肝癌死亡趋势分析

Trends in mortality of liver cancer in Wenzhou City from 2014 to 2022

目的了解2014—2022年浙江省温州市肝癌死亡趋势,为完善肝癌防控策略提供依据。方法通过温州市慢性病监测信息管理系统收集2014—2022年温州市肝癌死亡病例资料,计算粗死亡率,采用2010年全国第六次人口普查数据计算标化死亡率,采用平均年度变化百分比(AAPC)分析肝癌死亡变化趋势。结果2014—2022年温州市肝癌累计死亡22033例,占恶性肿瘤死亡的18.08%,居恶性肿瘤死亡第二位。肝癌粗死亡率为30.00/10万,标化死亡率为24.32/10万,呈下降趋势(AAPC=-2.812%、-5.742%,均P<0.05)。男性肝癌标化死亡率为36.66/10万,高于女性的11.21/10万(P<0.05),男性和女性肝癌标化死亡率呈下降趋势(AAPC=-5.702%、-5.521%,均P<0.05)。肝癌粗死亡率随年龄增长呈上升趋势(P<0.05),80~<85岁组粗死亡率最高,达145.12/10万。2014—2022年温州市<15岁、15~<45岁、45~<65岁和≥65岁组肝癌粗死亡率呈下降趋势(AAPC=-20.311%、-6.569%、-7.408%和-3.177%,均P<0.05)。结论2014—2022年温州市肝癌死亡率呈下降趋势,男性和老年人是肝癌死亡的高危人群,应针对危险因素加强预防。

Objective To analyze the trends in mortality of liver cancer in Wenzhou City,Zhejiang Province from 2014 to 2022,so as to provide the evidence for improving liver cancer control measures.Methods Data of liver can⁃cer mortality in Wenzhou City from 2014 to 2022 were collected from Wenzhou Chronic Disease Monitoring Informa⁃tion System.The crude mortality were estimated and standardized by the national population census data in China in 2010,and the trends in mortality of liver cancer were analyzed with average annual percent change(AAPC).Results There were 22033 liver cancer deaths from 2014 to 2022,accounting for 18.08%of malignant tumor deaths and ranking the second in malignant tumor deaths.The crude mortality of liver cancer was 30.00/105 and the standardized mortality was 24.32/105,both showing decreasing trends(AAPC=-2.812%and-5.742%,both P<0.05).The standard⁃ized mortality of liver cancer were higher in men than in women(36.66/105 vs.11.21/105,P<0.05),both showing de⁃creasing trends(AAPC=-5.702%and-5.521%,both P<0.05).The crude mortality of liver cancer appeared a tenden⁃cy towards a rise with age(P<0.05),with the highest crude mortality in the group aged 80 to 84 years,reaching 145.12/105.The crude mortality of liver cancer showed a tendency towards a decline among residents aged under 15 years,15 to 44 years,45 to 64 years and 65 years and above(AAPC=-20.311%,-6.569%,-7.408%and-3.177%,all P<0.05).Conclusions The mortality of liver cancer showed a tendency towards a decline in Wenzhou City from 2014 to 2022.Men and the elderly were high-risk groups for liver cancer deaths,and prevention should be strength⁃ened based on risk factors.