家庭照护者焦虑抑郁水平与乳腺癌术后辅助化疗患者生活质量的相关性

Correlation between anxiety,depression levels of family caregivers and quality of life of breast cancer patients with postoperative adjuvant chemotherapy

目的探讨乳腺癌术后辅助化疗患者的生活质量及其家庭照护者的焦虑抑郁水平,并分析两者的相关性。方法选取接受术后辅助化疗的女性乳腺癌患者200例及其家庭照护者进行问卷调查。采用医院焦虑抑郁量表(HADS)评估家庭照护者的焦虑抑郁水平,采用中文版乳腺癌患者生命质量测定量表(FACT-B)评估乳腺癌术后辅助化疗患者的生活质量,两者的相关性采用Spearman相关分析。结果共发放HADS问卷200份,收回190份,剔除无效问卷9份,获得有效问卷181份;共发放FACT-B问卷200份,收回192份,剔除无效问卷10份,获得有效问卷182份。选择两问卷均有效的168对问卷数据纳入最终统计分析,28.57%(48/168)的家庭照护者存在焦虑情绪,25.60%(43/168)的家庭照护者存在抑郁情绪,17.26%(29/168)的家庭照护者同时存在焦虑和抑郁情绪。家庭照护者的HADS焦虑分量表(HADS-A)和抑郁分量表(HADS-D)评分分别为5.0(3.0,8.0)分和4.0(2.0,8.0)分。乳腺癌术后辅助化疗患者的FACT-B总分为(101.86±19.11)分。家庭照护者HADS-A、HADS-D评分与乳腺癌术后辅助化疗患者FACT-B总分均呈负相关(r=-0.283、-0.346,P<0.05)。除焦虑水平与社会/家庭状况评分无相关性外,家庭照护者焦虑抑郁水平与乳腺癌术后辅助化疗患者FACT-B各维度评分均呈负相关(P<0.05)。结论乳腺癌术后辅助化疗患者家庭照护者焦虑抑郁现象颇为常见,可从多方面对患者生活质量产生负面影响,医护人员需重视家庭照护者的心理状态。

Objective To investigate the quality of life of breast cancer patients with postoperative adjuvant chemotherapy and the anxiety and depression levels of their family caregivers,and to analyze the correlation between them.Method A questionnaire survey was conducted among 200 female breast cancer patients who received postoperative adjuvant chemotherapy and their family caregivers.The hospital anxiety and depression scale(HADS)was used to evaluate the anxiety and depression levels of family caregivers,and the Chinese version of function assessment of cancer therapybreast(FACT-B)was used to evaluate the quality of life of breast cancer patients with postoperative adjuvant chemotherapy.The correlation between the anxiety and depression levels of family caregivers and quality of life of breast cancer patients were analyzed by Spearman correlation analysis.Result A total of 200 HADS questionnaires were sent out,190 were recovered,9 invalid questionnaires were excluded,and 181 valid questionnaires were obtained.A total of 200 FACTB questionnaires were sent out,192 were recovered,10 invalid questionnaires were excluded,and 182 valid questionnaires were obtained.A total of 168 pairs of valid questionnaires were included in the final statistical analysis,28.57%(48/168)of family caregivers had anxiety emotion,25.60%(43/168)had depression emotion,and 17.26%(29/168)had both anxiety and depression emotions.The HADS-anxiety subscale(HADS-A)and HADS-depression subscale(HADSD)scores of family caregivers were 5.0(3.0,8.0)points and 4.0(2.0,8.0)points,respectively.The total score of FACT-B in breast cancer patients with postoperative adjuvant chemotherapy was(101.86±19.11)points.The HADS-A and HADSD scores of family caregivers were negatively correlated with the total score of FACT-B in breast cancer patients with postoperative adjuvant chemotherapy(r=-0.283,-0.346,P<0.05).In addition to no correlation between anxiety level and social/family status score,anxiety and depression levels of family caregivers were negatively correlated with each dimensional score of FACT-B in breast cancer patients with postoperative adjuvant chemotherapy(P<0.05).Conclusion Anxiety and depression in family caregivers of breast cancer patients with postoperative adjuvant chemotherapy are quite common,which can have a negative impact on the quality of life of patients from various aspects.Medical staff should pay attention to the psychological state of family caregivers.