肺康复训练联合营养干预治疗慢性阻塞性肺病合并肌少症患者的临床疗效及对生活质量的影响

Clinical Efficacy of Pulmonary Rehabilitation Training Combined with Nutritional Intervention in the Treatment of Patients with Chronic Obstructive Pulmonary Disease Complicated with Sarcopenia and its Effect on Quality of Life

目的研究肺康复训练联合营养干预治疗慢性阻塞性肺病(COPD)合并肌少症患者的临床疗效,以及对其生活质量的影响。方法以2022年1月-2023年1月泰兴市人民医院收治的64例COPD合并肌少症患者为研究对象,经随机数字表法分为对照组(32例)与观察组(32例)。对照组接受肺康复训练,观察组在其基础上进行营养干预治疗,比较两组临床疗效、肺功能[用力肺活量(FVC)、第1s用力呼气容积(FEV_(1))、FEV_(1)/FVC]、营养状况[简易营养评价精法(MNA-SF)]、运动功能[6min步行试验(6MWT)、简易体能状况量表(SPPB)]、生活质量[圣·乔治医院呼吸问题调查问卷(SGRQ)、健康调查简表(SF-36)]。结果观察组治疗有效率为93.75%,高于对照组的75.00%(P<0.05)。两组治疗后FVC、FEV_(1)、FEV_(1)/FVC均高于治疗前,且观察组FVC、FEV_(1)、FEV_(1)/FVC高于对照组(P<0.05)。两组治疗后MNA-SF分数、6MWT结果、SPPB分数均大于治疗前,且观察组MNA-SF分数、6MWT结果、SPPB分数大于对照组(P<0.05)。两组治疗后SGRQ分数低于治疗前,SF-36分数高于治疗前,且观察组SGRQ分数低于对照组,SF-36分数高于对照组(P<0.05)。结论肺康复训练联合营养干预治疗COPD合并肌少症疗效确切,可提高患者肺功能,改善其营养状况与运动体能,有利于患者生活质量的提升。

Objective To study the clinical efficacy of pulmonary rehabilitation training combined with nutritional intervention in the treatment of patients with chronic obstructive pulmonary disease(COPD)complicated with sarcopenia and its effect on the quality of life.Methods A total of 64 patients with COPD complicated with sarcopenia admitted to Taixing People's Hospital from January 2022 to January 2023 were divided into control group(32 patients)and observation group(32 patients)by random number table method.The control group received pulmonary rehabilitation training,and the observation group received nutritional intervention on the basis of the control group.The clinical efficacy,pulmonary function[forced vital capacity(FVC),forced expiratory volume in the first second(FEV_(1)),FEV_(1)/FVC],nutritional status[Short-form Mini-Nutritional Assessment(MNA-SF)],motor function[6 min walking test(6MWT),Short Physical Performance Battery(SPPB)],quality of life[St.George's Respiratory Questionnaire(SCRQ),36-item Short-Form(SF-36)]were compared between the two groups.Results The effective rate of treatment in the observation group was 93.75%,which was higher than 75.00%in the control group(P<0.05).Affter treatment,FVC,FEV_(1) and FEV_(1)/FVC in the two groups were higher than those before treatment,and FVC,FEV_(1) and FEV_(1)/FVC in the observation group were higher than those in the control group(P<0.05).After treatment,the scores of MNA-SF,6MWT and SPPB in the two groups were higher than those before treatment,and the scores of MNA-SF,6MWT and SPPB in the observation group were higher than those in the control group(P<0.05).After treatment,the SGRQ score of the two groups was lower than that before treatment,and the SF-36 score was higher than that before treatment,and the SGRQ score of the observation group was lower than that of the control group,and the SF-36 score was higher than that of the control group(P<0.05).Conclusion Pulmonary rehabilitation training combined with nutritional intervention is effective in the treatment of COPD with sarcopenia,which can improve the lung function of patients,improve their nutritional status and physical fitness,and is conducive to the improvement of patients'quality of life.