中西医结合治疗肝郁气滞型乳腺增生的疗效观察

Observation on the therapeutic effect of combining traditional Chinese and Western medicine in the treatment of breast hyperplasia of liver depression and qi stagnation type

目的观察中西医结合治疗肝郁气滞型乳腺增生的疗效。方法60例肝郁气滞型乳腺增生患者,以随机数字表法分为对照组和观察组,每组30例。对照组患者接受西药疗法,观察组患者接受中西医结合治疗。比较两组临床疗效、内分泌激素指标[催乳素(PRL)、孕酮(P)、雌二醇(E_(2))、血清促黄体生成素(LH)]水平、症状(肿块大小、肿块范围、肿块硬度、疼痛程度)评分改善情况。结果治疗后,与对照组的73.33%比较,观察组的总有效率100.00%更高(P<0.05)。治疗后,与对照组的(28.38±1.66)ng/ml、(78.44±7.44)pg/ml比较,观察组的PRL(21.33±1.41)ng/ml、E_(2)(55.66±6.23)pg/ml更低,与对照组的(12.77±1.88)ng/ml、(10.92±1.13)mU/ml比较,观察组的P(15.22±2.03)ng/ml、LH(15.66±1.25)mU/ml更高(P<0.05)。治疗后,与对照组的(3.35±0.33)、(3.77±0.45)、(3.77±0.34)、(2.58±0.35)分比较,观察组的肿块大小评分(2.42±0.29)分、肿块范围评分(2.22±0.38)分、肿块硬度评分(2.59±0.29)分、疼痛程度评分(1.09±0.29)分更低(P<0.05)。结论肝郁气滞型乳腺增生患者接受中西医结合治疗能够有效提高治疗效果,改善内分泌激素水平,缓解各临床症状,临床应用价值显著。

Objective To observe the therapeutic effect of combining traditional Chinese and Western medicine in the treatment of breast hyperplasia of liver depression and qi stagnation type.Methods 60 patients with breast hyperplasia of liver depression and qi stagnation type were randomly divided into a control group and an observation group using a random number table method with 30 cases in each group.The control group received Western medicine therapy,while the observation group received combining traditional Chinese and Western medicine therapy.Both groups were compared in terms of clinical efficacy,endocrine hormone indicators[prolactin(PRL),progesterone(P),estradiol(E_(2)),serum luteinizing hormone(LH)]levels,and improvement of symptom(tumor size,tumor range,tumor hardness,and pain)scores.Results After treatment,the observation group had a higher total effective rate of 100.00%than 73.33%in the control group(P<0.05).After treatment,the observation group had PRL of(21.33±1.41)ng/ml and E_(2) of(55.66±6.23)pg/ml,which were lower than the control group's(28.38±1.66)ng/ml and(78.44±7.44)pg/ml;the observation group had P of(15.22±2.03)ng/ml and LH of(15.66±1.25)mU/ml,which were higher than the control group's(12.77±1.88)ng/ml and(10.92±1.13)mU/ml(P<0.05).After treatment,the observation group had tumor size of(2.42±0.29)points,tumor range of(2.22±0.38)points,tumor hardness of(2.59±0.29)points,and pain score of(1.09±0.29)points,which were lower than the control group's(3.35±0.33),(3.77±0.45),(3.77±0.34),and(2.58±0.35)points(P<0.05).Conclusion Combining traditional Chinese and Western medicine can effectively improve the treatment effect,improve endocrine hormone levels,alleviate various clinical symptoms,and have significant clinical application value in patients with breast hyperplasia of liver depression and qi stagnation type.