摘要
目的:分析丙卡特罗口服液治疗支气管哮喘的效果。方法:选取2021年3月—2022年4月黄冈市妇幼保健院收治的支气管哮喘患者76例作为研究对象,依据随机数字表法分为两组,各38例。对照组给予布地奈德联合孟鲁司特治疗,研究组给予丙卡特罗治疗,比较两组治疗效果。结果:研究组治疗总有效率高于对照组,差异有统计学意义(P=0.028)。治疗后,两组白细胞介素-6、降钙素原、C反应蛋白水平低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。治疗后,两组第1秒用力呼气容积及呼气峰值流速大于治疗前,且研究组大于对照组,差异有统计学意义(P<0.05)。研究组不良反应总发生率低于对照组,差异有统计学意义(P=0.015)。结论:丙卡特罗口服液治疗支气管哮喘的效果较好,可改善患者肺功能,减轻炎性反应,且安全性较好。
Objective:To analyze the effect of procaterol oral solution in the treatment of bronchial asthma.Methods:A total of 76 patients with bronchial asthma admitted to Huanggang Maternal and Child Health Hospital from March 2021 to April 2022 were selected as the study subjects.They were divided into two groups with 38 cases in each group according to the random number table method.The control group was treated with budesonide combined with montelukast,and the study group was treated with procaterol.The treatment effects of the two groups were compared.Results:The total effective rate of treatment in the study group was higher than that in the control group,and the difference was statistically significant(P=0.028).After treatment,the levels of interleukin-6,procalcitonin and C-reactive protein in the two groups were lower than those before treatment,and the levels in the study group were lower than those in the control group,with a statistically significant difference(P<0.05).After treatment,the forced expiratory volume in 1 second and peak expiratory flow velocity in the two groups were higher than those before treatment,and these indexes in the study group were higher than those in the control group,with a statistically significant difference(P<0.05).The total incidence of adverse reactions in the study group was lower than that in the control group,and the difference was statistically significant(P=0.015).Conclusion:Procaterol oral solution has a good effect in the treatment of bronchial asthma,and can improve lung function and reduce inflammatory reactions in patients,with good safety.
作者
王丽芳
Wang Lifang(Pharmacy Department,Huanggang Maternal and Child Health Hospital,Huanggang 438000,Hubei Province,China)
出处
《中国社区医师》
2024年第9期47-49,共3页
Chinese Community Doctors
关键词
支气管哮喘
孟鲁司特钠
丙卡特罗
炎性因子
肺功能
Bronchial asthma
Montelukast sodium
Procaterol
Inflammatory factor
Lung function