阿司匹林预防心血管疾病研究进展

Aspirin in the prevention of cardiovascular disease:a review

阿司匹林(ASA)广泛用于心血管疾病(CVD)的一级和二级预防,但应用策略存在较大争议。同时,在ASA预防CVD策略上,世界各国不尽相同:美国日趋谨慎,欧盟更关注ASA临床使用的获益,我国侧重于ASA对老年人CVD的预防效果。本文收集2005—2024年国内外发表的相关文献,对ASA在CVD预防中的应用、主要国家ASA预防CVD策略,以及慢性病患者等特殊群体ASA应用情况进行综述,为我国完善ASA预防CVD策略、规范ASA临床应用提供依据。

Aspirin(ASA)is widely used for primary and secondary prevention of cardiovascular disease(CVD),but its strategy of application is highly controversial.Meanwhile,in terms of ASA prevention strategies for CVD,countries around the world are different.The United States is becoming increasingly cautious,while the European Union tends to focus on the benefits of ASA clinical use.China is concerned about the effectiveness of ASA in preventing CVD in the elderly.This article reviews relevant literature published domestically and internationally from 2005 to 2024 for the ap-plication of ASA in CVD prevention,ASA prevention strategies for CVD in main countries and the application of ASA in special groups such as chronic disease patients,which provides a basis for improving ASA prevention strategies for CVD and standardizing clinical application of ASA in China.