小儿难治性肺炎支原体肺炎临床特点、实验室指标及高分辨CT影像特点分析

Clinical Characteristics,Laboratory Indicators,and High-resolution CT Features of Refractory Mycoplasma Pneumoniae Pneumonia in Children

目的分析小儿难治性肺炎支原体肺炎(MPP)临床特点、实验室指标及高分辨CT影像特点。方法回顾性分析2022年8月~2023年11月本院收治的121例MPP患儿为对象,其中66例难治性MPP患儿纳入为观察组,55例普通MPP患儿纳入为对照组,所有患儿均接受相关实验室检查、胸部CT扫描。比较两组患儿临床特征、实验室指标及CT影像特点。结果两组患儿性别、年龄比较差异无统计学意义(P>0.05);观察组发热持续时间、住院时间、呼吸音减低、肺部叩诊浊音症状占比显著高于对照组(P<0.05);观察组患儿C反应蛋白(CRP)、降钙素原(PCT)、白细胞计数(WBC)、乳酸脱氢酶(LDH)、免疫球蛋白(IgA)水平均显著高于对照组(P<0.05);观察组胸腔积液、肺不张、肺实变发生率高于对照组(P<0.05)。结论小儿难治性MPP患儿持续发热时间、呼吸音减低及肺部叩诊浊音情况与普通MPP患儿存在差异,此外CRP、PCT、WBC、LDH及IgA水平与普通MPP患儿存在差异;CT检查中胸腔积液、肺不张及肺实变发生率更高。

Objective To analyze the clinical characteristics,laboratory indicators,and high-resolution CT features of refractory Mycoplasma pneumoniae pneumonia(MPP)in children.Methods A total of 121 children with MPP who were admitted to the hospital from August 2022 to November 2023 were reviewed.Among them,66 children with refractory MPP were included in the observation group,and 55 children with common MPP were included in the control group.All children received relevant laboratory tests and chest CT scan.Clinical characteristics,laboratory indicators,and CT features of the two groups were comparatively analyzed.Results There was no statistically significant difference in gender or age between the two groups(P>0.05).The duration of fever,length of hospital stay,and the proportions of decreased respiratory sounds and dullness of lung percussion in the observation group were significantly longer/higher than those in the control group(P<0.05).The levels of C-reactive protein(CRP),procalcitonin(PCT),white blood cell count(WBC),lactate dehydrogenase(LDH),and immunoglobulin(IgA)in the observation group were significantly higher than those in the control group(P<0.05).The incidence rates of pleural effusion,atelectasis,and pulmonary consolidation in the observation group were higher than those in the control group(P<0.05).Conclusion Children with refractory MPP and those with common MPP have different clinical characteristics and laboratory indicators.The incidence rates of pleural effusion,atelectasis,and pulmonary consolidation are higher in children with MPP.