血府逐瘀汤加减治疗高血压病并发不寐的有效性及安全性分析

Effect and Safety Analysis of Modified Modified Decoction of Removing Blood Stasis For Hypertension Complicated with Insomnia

目的 探究分析中药组方血府逐瘀汤在高血压不寐患者治疗干预中的有效性及安全性。方法 选取2022年1月—2022年12月松原市中心医院接诊治疗的62例高血压并发不寐患者为研究对象,通过随机数字表法分为研究组(n=31)、对照组(n=31)。对照组患者采用西药对症治疗干预,研究组患者参照对照组用药方案,增加血府逐瘀汤加减治疗,比较两组患者匹兹堡睡眠质量指数评分(PSQI)、生活质量评分、临床有效率、治疗安全性指标。结果 治疗后研究患者PSQI评分均低于对照组(P<0.05);治疗后研究组患者生活质量评分高于对照组(P<0.05);治疗后研究组患者临床有效率高于对照组(P<0.05);用药后两组患者均未产生明显严重的不适感(P>0.05)。结论 高血压病并发不寐患者采用血府逐瘀汤加减治疗可改善睡眠质量,患者的生活质量能够得到明显改善,总体疗效突出,患者能够耐受药物,因此可将该药物广泛应用于临床。

Objective To explore and analyze effect and safety of traditional Chinese medicine formula modified decoction of removing blood stasis in treatment intervention of hypertensive insomnia patients.Methods The paper chose 62 hypertensive patients with insomnia in Songyuan City Central Hospital from January 2022 to December 2022,and divided them into study group(n=31) and control group(n=31)with random number table method.Control group was treated with Western medicine for symptomatic intervention,while study group with modified modified decoction of removing blood stasis according to control group medication schem.Pittsburgh Sleep Quality Index(PSQI),life quality scores,clinical effective rate,and treatment safety indicators were compared between two groups.Results After treatment,PSQI scores of study group were lower than control group(P<0.05).Life quality scores of study group after treatment were lower than control group(P<0.05).After treatment,clinical effective rate of study group was higher than control group(P<0.05).After medication,neither group of patients experienced significant and severe discomfort(P>0.05).Conclusion Modified decoction of removing blood stasis can improve sleep quality and improve life quality of hypertension patients complicated with insomnia significantly,with great overall curative effect,patients can tolerate the medication,which can be widely applied in clinical practice.