奥硝唑合剂用于牙体牙髓病患者辅助填充治疗对其临床症状及生活质量的改善效果

Improvement Effect of Metronidazole Mixture on Clinical Symptoms and Life Quality for Patients with Dental Pulp Disease As an Auxiliary Filling Therapy

目的 对奥硝唑合剂在牙体牙髓病辅助填充治疗中对患者临床症状及生活质量的改善效果进行分析。方法 选择2021年6月—2022年12月本院收治的106例牙体牙髓病患者为观察对象,通过数字随机分配方式分成对照组和实验组,每组53例。两组均给予常规治疗,在此基础上,实验组加奥硝唑合剂辅助填充治疗,观察两组疗效情况。结果 对照组治疗后临床疗效总有效率是81.13%,不良反应的总发生率是18.87%,复发率是16.98%;实验组总有效率、不良反应发生率及复发率分别是96.23%、5.67%、1.87%,两组相比差异有统计学意义(P<0.05);治疗后两组患者咀嚼功能评分、咬合力、咀嚼效能及hs-CRP、IL-6、sICAM-1等水平均比治疗前有所改善(P<0.05),但实验组效果均优于对照组(P<0.05)。结论 对牙体牙髓病使用奥硝唑合剂辅助填充治疗不但可以有效提高疗效,还可以快速改善临床症状,提高患者生活质量,推广价值高。

Objective To analyze improvement effect of metronidazole mixture on clinical symptoms and life quality of patients in auxiliary filling treatment of dental pulp disease.Methods The paper chose 106 patients with dental pulp disease from June 2021 to December 2022 as observation subjects,and divided them into control group of 53 cases and experimental group of 53 cases randomly,with routine treatment.Experimental group was supplemented with metronidazole mixture for filling treatment on the basis.Curative effect between two groups was observed.Results Total effective rate of clinical effect in control group after treatment was 81.13%,total incidence of adverse reactions was 18.87%,recurrence rate was 16.98%.Total effective rate,incidence of adverse reactions,and recurrence rate in experimental group was 96.23%,5.67%,and 1.87% respectively,with P<0.05.After treatment,chewing function scores,bite force,chewing efficiency,hs CRP,IL-6,sICAM-1 and other levels were better than before treatment(P<0.05),experimental group showed better results than control group(P<0.05).Conclusion Metronidazole mixture can effectively improve curative effect,clinical symptoms,life quality for dental pulp disease as an adjuvant filling therapy,which has high promotion value.