硫辛酸联合甲钴铵治疗糖尿病周围神经病变的疗效探讨

Study on the Efficacy of Lipoic Acid Combined with Methylcobalamin in the Treatment of Diabetic Peripheral Neuropathy

目的 研究分析在糖尿病周围神经病变的治疗中采用硫辛酸联合甲钴胺干预的疗效。方法 选取2022年8月—2023年3月本院收治的90例糖尿病周围神经病变患者为研究对象,按照收治时间先后分为对照组及观察组,对照组接受常规降糖药以及甲钴胺进行治疗,观察组则在对照组基础上加入硫辛酸进行治疗,对比两组临床疗效、神经传导速度以及症状改善情况。结果 观察组临床总有效率明显高于对照组(P<0.05);观察组的神经传导速度快于对照组(P<0.05);观察组的相关症状缓解明显优于对照组(P<0.05)。结论 在糖尿病周围神经病变患者临床治疗中采用硫辛酸联合甲钴胺的模式可明显提升临床疗效,改善患者相关症状,对于患者预后具有重要意义。

Objective To study and analyze the therapeutic effect of lipoic acid combined with methylcobalamin in the treatment of diabetic peripheral neuropathy.Methods 90 patients with diabetic peripheral neuropathy who received treatment in our hospital from August 2022 to March 2023 were divided into control group and observation group according to the time of admission.The control group received routine hypoglycemic drugs and methylcobalamin for treatment.The observation group was treated with lipoic acid on the basis of the control value,and the clinical efficacy,nerve conduction velocity and symptom improvement of the two groups were compared.Results The total clinical effective rate of the observation group was 97.78%,which was significantly higher than that of the control group(71.11%)(P<0.05).The nerve conduction velocity of the observation group was faster than that of the control group(P<0.05).The remission of related symptoms in observation group was significantly better than that in control group(P<0.05).Conclusion In the clinical treatment of diabetic peripheral neuropathy patients,the combination of lipoic acid and methylcobalamin can significantly improve the clinical efficacy and improve the related symptoms of patients,which is of great significance for the prognosis of patients.