光动力疗法辅助治疗中度慢性牙周炎患者的临床疗效

Clinical Effect of Photodynamic Therapy in the Treatment of Moderate Chronic Periodontitis

【目的】探讨光动力疗法(PDT)辅助治疗中度慢性牙周炎患者的临床疗效。【方法】选择2021年1月至2023年9月在河南大学赛思口腔医院诊治的26例中度慢性牙周炎患者,从每个患者中选取双侧牙周组织破坏程度接近的2颗同名牙,并按照随机数字表法分为观察组[采用根面平整术(SRP)联合PDT治疗]和对照组(采用SPR治疗),每组26颗牙。两组均行口腔卫生宣教及龈上洁治术,1周后(治疗前)记录牙周探诊深度(PD)、出血指数(BI)和探诊出血(BOP)情况,所有PD≥4 mm的牙齿均进行SRP,比较两组治疗前、治疗6周后、治疗12周后PD、BI及BOP阳性率。【结果】两组治疗前PD、BI及BOP阳性率比较,差异无统计学意义(P>0.05);两组治疗6周后、治疗12周后PD、BI及BOP阳性率均显著低于治疗前,差异具有统计学意义(P<0.05);且观察组治疗6周后、治疗12周后PD、BI及BOP阳性率均显著低于对照组,差异有统计学意义(P<0.05)。【结论】PDT作为SPR的辅助治疗方法,可在短期内降低PD,减轻牙龈炎症及牙龈出血情况,比单纯SPR治疗临床效果好。

【Objective】To investigate the clinical effect of photodynamic therapy(PDT)in the treatment of moderate chronic periodontitis.【Methods】A total of 26 patients with moderate chronic periodontitis diagnosed and treated in SATH Hospital of Stomatology Henan University from January 2021 to September 2023 were selected.Two teeth with the same name with similar damage degree of bilateral periodontal tissue were selected from each patient.They were divided into the observation group(treated with SRP combined with PDT)and the control group(treated with SPR alone)according to random number table method,with 26 capsules in each group.Oral hygiene education and supragingival cleaning were performed in both groups.Periodontal probing depth(PD),bleeding index(BI)and probing bleeding(BOP)were recorded 1 week later(before treatment),and SRP was performed on all teeth with PD≥4 mm.The positive rates of PD,BI and BOP were compared between the two groups before treatment,6 weeks after treatment and 12 weeks after treatment.【Results】Before treatment,there was no significant difference in the positive rates of PD,BI and BOP between two groups(P>0.05).The positive rates of PD,BI and BOP after 6 weeks and 12 weeks of treatment were significantly lower than before treatment,with statistical significance(P<0.05).The positive rates of PD,BI and BOP in the observation group were significantly lower than those in the control group after 6 weeks and 12 weeks of treatment,with statistical significance(P<0.05).【Conclusion】PDT,as an adjunct therapy for SPR,can reduce PD in the short term,relieve gingival inflammation and gingival bleeding.It has better clinical effect than SPR alone.