美容整形清创缝合术联合牛碱性成纤维细胞生长因子对颌面部外伤的治疗效果

Effect of Cosmetic Debridement and Suture Combined with Bovine Basic Fibroblast Growth Factor in the Treatment of Maxillofacial Trauma

目的分析颌面部外伤患者采取美容整形清创缝合术、牛碱性成纤维细胞生长因子共同治疗的预后情况。方法随机选取2021年1月—2023年2月滕州市中医医院收治的颌面部外伤患者100例作为研究对象,通过随机抽签方式分组,对照组50例使用美容整形清创缝合术,观察组50例使用美容整形清创缝合术联合牛碱性成纤维细胞生长因子,对比两组治疗效果。结果观察组临床总疗效为96.00%,高于对照组(80.00%),差异有统计学意义(χ^(2)=6.060,P<0.05);观察组术后3 d血清表皮生长因子高于对照组,且肿瘤坏死因子-α、白介素-6低于对照组,差异有统计学意义(P均<0.05);观察组术后瘢痕长度、愈合时间短于对照组,且双向瘢痕评分量表、温和华评分表低于对照组,差异有统计学意义(P均<0.05);观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论予以美容整形清创缝合术治疗颌面部外伤的同时,配合牛碱性成纤维细胞生长因子可以提高患者临床疗效,其恢复效果更好、并发症发生率更低,有助于改善各种临床指标。

Objective To analyze the prognosis of patients with maxillofacial trauma treated with cosmetic debridement and suture combined with bovine basic fibroblast growth factor.Methods 100 patients with maxillofacial trauma treated by Tengzhou Hospital of Traditional Chinese Medicine from January 2021 to February 2023 were randomly selected as research objects.By random drawing,fifty cases in the control group were treated with cosmetic debridement and suturing,and fifty cases in the observation group were treated with cosmetic debridement and suturing combined with bovine basic fibroblast growth factor.The therapeutic effect of the two was compared.Results The total clinical efficacy of observation group was 96.00%,higher than that of control group(80.00%),and the difference was statistically significant(χ^(2)=6.060,P<0.05).The serum epidermal growth factor of observation group was higher than that of control group at 3 days after operation,and tumor necrosis factor-αand interleukin-6 were lower than that of control group,and the differences were statistically significant(all P<0.05).The postoperative scar length and healing time in the observation group were shorter than those in the control group,and the patient and observer scar scale and vinovka snaiperskaja spetsialnaya were lower than those in the control group,and the differences were statistically significant(both P<0.05).The complication rate of observation group was lower than that of control group,and the difference was statistically significant(P<0.05).Conclusion In the treatment of maxillofacial trauma by cosmetic debridement and suture,bovine basic fibroblast growth factor can improve the clinical efficacy of patients with better recovery effect and lower complication rate,which is helpful to improve various clinical indicators.