维生素B_(6)联合铝碳酸镁治疗孕妇妊娠剧吐的临床有效率及安全性的分析

Clinical Efficacy and Safety of Vitamin B_(6) Combined with Aluminum Magnesium Carbonate in the Treatment of Hyperemesis Gravidarum in Pregnant Women

目的探究维生素B_(6)联合铝碳酸镁治疗孕妇妊娠剧吐的临床有效率及安全性。方法随机于2021年3月—2022年3月选取晋江市中医院收治的50例妊娠剧吐孕妇为研究对象,利用统计学软件生成序列后随机分为对照组及观察组,各25例。对照组予以维生素B_(6)治疗,观察组予以维生素B_(6)联合铝碳酸镁治疗。对比两组治疗有效率、临床症状及用药安全性。结果观察组治疗总有效率(96.00%)高于对照组(76.00%),差异有统计学意义(χ^(2)=4.153,P<0.05);观察组电解质恢复时间、补液时间、酮体转阴时间、剧吐消失时间均短于对照组,差异有统计学意义(t=2.377、2.437、2.305、3.424,P均<0.05);观察组不良反应发生率均低于对照组,差异有统计学意义(P<0.05)。结论孕妇妊娠剧吐给予维生素B_(6)联合铝碳酸镁治疗有助于提高临床治疗有效率和安全性,有效改善临床症状。

Objective To explore the clinical efficacy and safety of vitamin B_(6) combined with aluminum magnesium carbonate in the treatment of hyperemesis gravidarum in pregnant women.Methods 50 pregnant women with hyperemesis gravidarum admitted to Jinjiang Hospital of Traditional Chinese Medicine from March 2021 to March 2022 were selected randomly as the study objects,and the sequences were generated by statistical software were randomly divided into control group and observation group,with 25 cases in each group.The control group was treated with vitamin B_(6),and the observation group was treated with vitamin B_(6) combined with aluminum magnesium carbonate.The clinical efficacy,clinical symptoms and drug safety of the two groups were compared.Results The total effective rate of observation group(96.00%)was higher than that of control group(76.00%),and the difference was statistically significant(χ^(2)=4.153,P<0.05).Electrolyte recovery time,fluid rehydration time,ketone negative transition time and hyperemesis disappearance time in observation group were shorter than those in control group,with statistical significance(t=2.377,2.437,2.305,3.424,all P<0.05).The incidence of adverse reactions in observation group was lower than that in control group,and the difference was statistically significant(P<0.05).Conclusion The treatment of vitamin B_(6) combined with aluminum magnesium carbonate in hyperemesis gravidarum prognant women can help improve the efficiency and safety of clinical treatment,effectively improve clinical symptoms.