黄芩汤联合运动疗法治疗创伤性脊髓损伤临床研究

Clinical Study on Huangqin Decoction Combined with Exercise Therapy for Traumatic Spinal Cord Injury

目的:观察黄芩汤联合运动疗法治疗创伤性脊髓损伤(TSCI)的疗效。方法:选取42例TSCI患者,按随机数字表法分为对照组及试验组各21例。对照组采用运动疗法治疗,试验组在此基础上加用黄芩汤进行治疗,2组均治疗3周。比较2组治疗前后美国脊髓损伤学会(ASIA)神经功能评分、脊髓功能独立性量表(SCIM-Ⅲ)评分、日常生活能力(ADL)评分、Berg平衡量表(BBS)评分、中医证候积分的变化。结果:治疗后,2组ASIA运动评分、感觉评分均较治疗前升高(P<0.05),试验组上述2项评分均高于对照组(P<0.05)。治疗后,2组自我照顾、呼吸和括约肌管理、移动能力及SCIM-Ⅲ总分均较治疗前升高(P<0.05),试验组上述4项评分均高于对照组(P<0.05)。治疗后,2组ADL评分、BBS评分均较治疗前升高,2组ADL评分比较,差异有统计学意义(P<0.05),中医证候积分均较治疗前下降(P<0.05);试验组ADL评分、BBS评分均高于对照组,2组ADL评分比较,差异有统计学意义(P<0.05),中医证候积分低于对照组(P<0.05)。结论:黄芩汤联合运动疗法治疗TSCI能缓解临床症状,提高运动能力、平衡能力及日常生活能力,提升生活质量。

Objective:To observe the curative effect of the Huangqin Decoction combined with exercise therapy on traumatic spinal cord injury(TSCI).Methods:A total of 42 TSCI patients were selected and divided into the control group and the trial group according to random number table method,with 21 patients in each group.The control group was treated with exercise therapy,and the trial group was additionally treated with Huangqin Decoction based on exercise therapy.Both groups were treated for 3 weeks.The changes in the scores of neural function in American Spinal Injury Association(ASIA),Spinal Cord Independence Measure(SCIM-Ⅲ),Activity of Daily Living(ADL),Berg Balance Scale(BBS)and traditional Chinese medicine(TCM)syndrome scores were compared before and after treatment between the two groups.Results:After treatment,the motor scores and sensory scores in ASIA in the two groups were increased when compared with those before treatment(P<0.05),and the above two scores in the trial group were higher than those in the control group(P<0.05).After treatment,the scores of self-care,respiration and sphincter management,mobility and the total scores of SCIM-Ⅲin the two groups were increased when compared with those before treatment(P<0.05),and the above four scores in the trial group were higher than those in the control group(P<0.05).After treatment,the ADL and BBS scores in the two groups were increased when compared with those before treatment,comparison of ADL scores between two groups,differences being significant(P<0.05),and the TCM syndrome scores were decreased when compared with those before treatment(P<0.05);the ADL and BBS scores in the trial group were higher than those in the control group,two groups ADL scores comparison,the difference being significant(P<0.05),and the TCM syndrome scores in the trial group were lower than those in the control group(P<0.05).Conclusion:Huangqin Decoction combined with exercise therapy can alleviate clinical symptoms of TSCI patients,improve motor,balance and daily life skills,and enhance quality of life.