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女性血脂异常对辅助生殖助孕结局影响的研究进展

Research Progress on the Impact of Female Dyslipidemia on the Outcome of Assisted Reproduction Treatment
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摘要 诸多研究表明,代谢异常对女性生育结局具有显著影响。对于接受辅助生殖技术(assisted reproductive technology,ART)治疗的代谢异常女性患者,其临床结局应受到高度重视。该文围绕女性血脂代谢异常,综述其在ART治疗中对助孕结局、母婴围产期安全以及后代健康状况的影响,并探讨相关机制和治疗策略的最新研究进展,旨在为妇幼健康领域的诊疗提供更多参考信息和临床策略,以期提升代谢异常女性在接受ART治疗时的助孕效果与安全性,为这一特殊人群的健康生育保驾护航。 Numerous studies have demonstrated that metabolic abnormalities significantly impact the reproductive outcomes.For women with metabolic abnormalities undergoing ART(assisted reproductive technology)treatment,their clinical outcomes should be highly prioritized.This article focuses on the effects of dyslipidemia on the ART treatment outcomes,maternal-fetal health,and offspring well-being.The latest research progress on relevant mechanisms and new therapeutic approaches is also discussed.The aim is to provide more reference information and clinical strategies to improve ART treatment outcomes and ensure the healthy reproduction of this special population.
作者 兰婷 高姗姗 赵世刚 LAN Ting;GAO Shanshan;ZHAO Shigang(State Key Laboratory of Reproductive Medicine and Offspring Health,Institute of Women,Children and Reproductive Health,National Research Center for Assisted Reproductive Technology and Reproductive Genetics,Shandong University,Jinan 250012,China)
出处 《中国细胞生物学学报》 CAS CSCD 2024年第4期682-690,共9页 Chinese Journal of Cell Biology
基金 国家重点研发计划(批准号:2021YFC2700400、2022YFC2704404) 中国医学科学院医学科学创新基金(批准号:2021-I2M-5-001)资助的课题。
关键词 辅助生殖 血脂 卵母细胞 胚胎 子代 assisted reproduction serum lipid oocytes embryos offspring
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