肠道菌群对卵巢衰老的影响及其潜在的机制

The Effect of Gut Microbiota on Ovarian Aging and Its Potential Mechanism

卵巢衰老是影响女性生殖健康的关键因素,与生育能力下降、更年期提前等问题密切相关。最新研究显示,肠道菌群的变化可能通过肠道-卵巢轴影响卵巢的功能和衰老进展。这些研究进展不仅提供了从肠道菌群角度探讨女性生殖健康的新视角,也为卵巢衰老的预防和干预提出了新的策略。该文回顾了近年来肠道菌群对卵巢衰老影响及其机制方面的研究进展,强调了研究肠道菌群与卵巢衰老相互作用的重要性。加强肠道菌群与卵巢衰老的关联机制研究不仅有助于深化对卵巢衰老机制的理解,也为研发新的治疗策略提供了理论和实验基础。

Ovarian aging is a key factor affecting women’s reproductive health,closely related to decreased fertility and early menopause.Recent studies indicated that alteration of gut microbiota influenced ovarian function and aging processes through microbiota-gut-ovary axis.These findings not only offer a new perspective for exploring women’s reproductive health through gut microbiota,but also propose novel strategies for the prevention and intervention of ovarian aging.This review summarized the recent research progress regarding connection between gut microbiota and ovarian aging,discussed the potential impact of gut microbiota on ovarian function,and the possible association between gut microbiota imbalance and ovarian aging-related diseases.Exploring the relationship between gut microbiota and ovarian aging is essential to enhance comprehension of the mechanisms involved in ovarian aging,laying the groundwork for the development of novel therapeutic approaches for preventing ovarian aging.