布洛芬缓释胶囊在成年女性呼吸道感染伴发热中的退热效果

Antipyretic Effect of Ibuprofen Sustained-Release Capsules in Adult Female Respiratory Tract Infections with Fever

目的探讨成年女性呼吸道感染伴发热采用药物布洛芬缓释胶囊治疗的效果。方法以2020年1月—2023年10月西苑医院济宁医院接诊成年女性呼吸道感染伴发热患者80例作为本次进行治疗分析的对象,以随机数字表法分组,对照组(40例)采用药物对乙酰氨基酚片治疗,观察组(40例)采用药物布洛芬缓释胶囊治疗;比较两组退热效果,监测两组患者用药前后不同时间点体温情况、用药前后炎症指标以及患者用药后的不良反应发生率。结果观察组呼吸道感染伴发热患者通过布洛芬治疗后退热效果优于对照组(P<0.05);观察组患者用药后1 h、2 h、3 h及6 h体温均低于对照组(均P<0.05);观察组患者用药后炎症指标(白细胞计数、C反应蛋白、白细胞介素6)检测结果均低于对照组,不良反应总发生率低于对照组(均P<0.05)。结论成年女性患呼吸道感染伴发热疾病,服用布洛芬缓释胶囊治疗,具有较好退热效果,同时不良反应少。

Objective To explore the therapeutic effect of ibuprofen sustained-release capsules on adult female respiratory tract infections with fever.Methods From January 2020 to October 2023,80 cases of adult female patients with respiratory tract infection with fever received by Xiyuan Hospital Jining Hospital were taken as the object of the present treatment and analysis,grouped by randomized numerical table,the control group(40 cases)was treated with the drug acetaminophen tablets,and the observation group(40 cases)was treated with the drug ibuprofen extendedrelease capsule;compare the antipyretic effect of the two groups,and monitor the temperature of the patients in the two groups at different time points before and after the use of medication,the inflammation index before and after the use of medication,and the incidence of adverse reactions in the patients after the use of medication.Results The patients with respiratory tract infection with fever in the observation group had better fever-reducing effect than the control group after treatment with ibuprofen(P<0.05);the temperature of the patients in the observation group was lower than that of the control group at 1 h,2 h,3 h,and 6 h after the administration of the drug(all P<0.05);the results of the inflammatory indexes(leukocyte count,C-reactive protein,and interleukin-6)of the patients in the observation group were lower than that of the control group after the administration of the drug,and the total incidence rate of adverse reactions was lower than that of the control group(all P<0.05).Conclusions Taking ibuprofen sustained-release capsules for the treatment of respiratory infections with fever in adult women has a good antipyretic effect and fewer adverse reactions.