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肠道菌群参与糖尿病肾病的机制研究进展

Research progress on the mechanism of gut microbiota participating in diabetes nephropathy
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摘要 随着糖尿病患病率升高,糖尿病肾病的预防和治疗已成为世界性难题。糖尿病肾病发生发展的分子机制目前尚不明确,但近年来诸多研究表明,肠道菌群在糖尿病肾病的进展中发挥重要作用。综述了肠道菌群参与糖尿病肾病的机制研究进展。 With the increasing prevalence of diabetes,the prevention and treatment of diabetes nephropathy have become a worldwide problem.The molecular mechanism of the occurrence and development of diabetes nephropathy is still unclear,but many studies in recent years have shown that gut microbiota plays an important role in the progress on diabetes nephropathy.The research progress on the mechanism of gut microbiota participating in diabetes nephropathy was reviewed in this article.
作者 徐飞 陈瑾 鲁育含 李志勇 XU Fei;CHEN Jin;LU Yuhan;LI Zhiyong(Department of Pharmacology,School of Pharmacy,First Affiliated Hospital of Naval Medical University,Shanghai 200433,China;Department of Endocrinology,First Affiliated Hospital of Naval Medical University,Shanghai 200433,China;Department of Health Care,Laoshan Hospital,Qingdao University,Qingdao 266000,China)
出处 《药学实践与服务》 CAS 2024年第5期181-184,197,共5页 Journal of Pharmaceutical Practice and Service
基金 上海市科技创新行动计划(201409004600) 上海市自然科学基金(23ZR1477400)。
关键词 糖尿病 糖尿病肾病 肠道菌群 肠道通透性 diabetes diabetes nephropathy intestinal flora intestinal permeability
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