改良宫颈环形电切术与传统宫颈环形电切术在宫颈高度鳞状上皮内瘤变患者中的效果比较

Comparison on the effect of modified loop electrosurgical excision procedure and traditional loop electrosurgical excision procedure in women with cervical high-grade squamous intraepithelial lesions

目的比较宫颈高度鳞状上皮内瘤变(HSIL)患者采用改良宫颈环形电切术(LEEP)与传统宫颈环形电切术的疗效。方法选取2021年6月至2022年6月在泉州玛珂迩妇产医院阴道镜室的第一次接受LEEP治疗的60例HISL育龄期女性患者作为研究对象,根据术中手术方式的不同将其分为改良LEEP术组(30例)和传统LEEP术组(30例)。比较两组患者的术中阴道出血量、术后阴道出血量、手术时间、宫颈再生率。结果改良LEEP术组的手术时间短于传统LEEP术组,差异有统计学意义(P<0.05)。改良LEEP术组的术中阴道出血量少于传统LEEP术组,差异有统计学意义(P<0.05)。改良LEEP术组的术后1d~1周发生的再出血率低于传统LEEP术组,差异有统计学意义(P<0.05)。改良LEEP组的术后12月宫颈长度测量长于传统LEEP组,差异有统计学意义(P<0.05)。改良LEEP组的术后宫颈再生率优于传统LEEP组,差异有统计学意义(P<0.05)。结论对HSIL患者采用改良LEEP术,能够有效降低术中出血及术后出血,缩短手术时间,提高宫颈再生率,值得推广应用。

Objective To compare the effects of modified loop electrosurgical excision procedure(LEEP)and traditional LEEP in women with cervical high-grade squamous intraepithelial lesions(HSIL).Methods A total of 60 women of child-bearing age with HISL,which was diagnosed in Department of Vaginoscopy in Macare Women's Hospital from June 2021 to June 2022,received LEEP as the first time were enrolled.They were divided into the modified LEEP group(30 cases)and the traditional LEEP group(30 cases)according to the different operative methods.The amount of vaginal hemorrhage during and after the operation,the operation time,the cervix length after surgery and cervical regeneration rate were recorded and compared between the two groups.Results The operation time in the modified LEEP group was shorter than that in the tra-ditional LEEP group,the difference was statistically significant(P<0.05).The amount of vaginal hemorrhage during the op-eration in the modified LEEP group was less than that in the traditional LEEP group,the difference was statistically signifi-cant(P<0.05).The post operation vaginal hemorrhage at day one to a week in the modified LEEP group was lower than that in the traditional LEEP group,the difference was statistically significant(P<0.05).At 12 months after surgery,the cervix length in the modified LEEP group was longer than that in the traditional LEEP group,the difference was statistically significant(P<0.05).The postoperative cervical regeneration rate in the modified LEEP group was better than that in the traditional LEEP group,the difference was statistically significant(P<0.05).Conclusion In the treatment of the women with HSIL,the modified LEEP can effectively reduce the amount of vaginal hemorrhage during and after operation,shorten the operation time,and increase the postoperative cervix regeneration rate,which is worthy of its promotion and application.