二硫化硒的制备及其在洗护领域的应用研究进展

Research progress on the preparation of selenium disulfide and its application in the field of toiletries

二硫化硒是硫化硒(SemSn)混合物的统称,具有多元环结构,不同环结构之间可相互转化。二硫化硒常用熔融法、化学法合成,而纳米二硫化硒常用电化学法和绿色合成法制备,其常用的表征方法有X射线衍射分析(XRD)、扫描电镜(SEM)、透射电镜(TEM)、X射线能量光谱仪(EDS)、动态光散射(DLS)和傅里叶红外光谱(FT-IR)。二硫化硒属于细胞生长抑制剂和角质溶解剂,具有抗皮脂溢出、抗真菌及细菌的作用,能抑制核分裂,造成表皮细胞更替减少,起到止痒、消炎、减少脱屑的作用,常用于治疗脂溢性皮炎和花斑藓。硫和硒都是具有多种原子价位的元素,既可表现还原性,又可表现氧化性,其潜能让二硫化硒的分子结构、性能特点及应用开发成为研究热点。本文综述了二硫化硒性质、结构特点、制备方法、表征及其在洗护领域的应用,并对其未来发展趋势进行了展望。

Selenium disulfide is a generic term for mixtures of SemSn with a polycyclic ring structure,which has different ring structures interconverting with each other in the molten and solution states.Selenium disulfide is commonly synthesized by fusion and chemical methods,while nanosized selenium disulfide is commonly synthesized by electrochemical and green synthesis methods.Its commonly used characterization methods are X-ray diffraction analysis(XRD),Scanning electron microscope(SEM),Transmission electron microscope(TEM),X-ray energy spectrometry(EDS),Dynamic light scattering(DLS)and Fourier transform infrared spectrometer(FT-IR).Selenium disulfide is a cell growth inhibitor and a keratolytic agent,with anti-seborrhea,anti-fungal and anti-bacterial effects,which can inhibits nuclear division,resulting in reduced epidermal cell turnover.It is commonly used in the treatment of seborrheic dermatitis and lichen planus because of its antipruritic,anti-inflammatory and anti-dandruff properties.Sulfur and selenium are both elements with multiple atomic valences that can exhibit both reducing and oxidizing properties.Their potential has made the molecular structure,performance characteristics and application development of selenium disulfide a research hotspot.This paper reviews the selenium disulfide properties,structural features,preparation methods,characterization and applications,and gives an outlook on its future development trend.