朱琏抑制Ⅱ型针法治疗肺癌化疗后胃肠道反应的临床研究

Clinical Study of ZHU Lian's Inhibition TypeⅡ Acupuncture in Treatment of Gastrointestinal Reaction after Chemotherapy for Lung Cancer

目的:观察朱琏抑制Ⅱ型针法治疗肺癌化疗后胃肠道反应的临床疗效。方法:将90例患者随机分为西药组、普通针刺组和治疗组,每组30例,西药组采用盐酸甲氧氯普胺注射联合盐酸托烷司琼治疗,同时予盐酸洛哌丁胺胶囊口服;普通针刺组在西药组基础上采用普通针刺治疗,针刺选取内关、足三里、中脘和上巨虚穴;治疗组在西药组的基础上,采用朱琏抑制Ⅱ型针法治疗,选穴同普通针刺组。分别于治疗后第1天、3天与5天,比较3组患者胃肠道反应(恶心呕吐、腹泻)改善情况。结果:3组治疗后恶心呕吐症状、腹泻症状显著改善,差异具有统计学意义(P<0.05);治疗后,治疗组的恶心呕吐、腹泻症状改善程度优于西药组、普通针刺组,差异具有统计学意义(P<0.05)。治疗组治疗总有效率93.33%(28/30),高于西药组的53.33%(16/30)、普通针刺组的73.33%(22/30),差异具有统计学意义(P<0.05)。治疗组白细胞计数降低程度较西药组、普通针刺组少,差异具有统计学意义(P<0.05),3组红细胞计数、血小板计数比较,差异无统计学意义(P>0.05)。结论:运用朱琏抑制Ⅱ型针法可有效缓解肺癌化疗后胃肠道反应,疗效显著。

Objective:To observe the clinical effect of ZHU Lian's typeⅡ inhibition acupuncture in treatment of gastrointestinal reaction after chemotherapy for lung cancer.Methods:90 patients were randomly divided into the Western medication group,the conventional acupuncture group and the treatment group,with 30 cases in each group.The Western medication group was treated with metoclopramide hydrochloride injection combined with toranisetron hydrochloride,and loperamide hydrochloride capsules orally;on which basis,the conventional acupuncture group was treated with conventional needling Neiguan(PC6),Zusanli(ST36),Zhongwan(RN12) and Shangjuxu(ST37),whereas the treatment group was treated with ZHU Lian's typeⅡ inhibition acupuncture,the acupoints chosen were the same as in the conventional acupuncture group.The improvement of gastrointestinal reactions,including nausea,vomiting and diarrhea,was compared among the three groups on 1 st,3 rd and 5 th day of treatment.Results:In terms of gastrointestinal reaction,the symptoms of nausea,vomiting and diarrhea were significantly improved in the three groups after the treatment(P<0.05),and the improvements were more significant in the treatment group than those in the Western medication group and the conventional acupuncture group(P<0.05).In terms of total effective rate,it was 93.33%(28/30) in the treatment group,which was higher than 53.33%(16/30) in the Western medication group and 73.33%(22/30) in the conventional acupuncture group(P<0.05).In terms of safety,the reduction of white blood cells was less in the treatment group than that in the Western medication group and the conventional acupuncture group(P<0.05);there were no statistical differences in the amount of red blood cells and platelets among the three groups(P>0.05).Conclusion:ZHU Lian's typeⅡ inhibition acupuncture can effectively relieve gastrointestinal reactions after chemotherapy and improve the curative effect.