1例高分化精索脂肪肉瘤1年内3次手术治疗报告并文献复习

Surgical treatment of liposarcoma of spermatic cord 3 times in 1 year:a case report and literature review

目的探讨高分化精索脂肪肉瘤的临床特点及诊治方法。方法回顾性分析1例多次复发高分化精索脂肪肉瘤患者的临床资料,结合相关文献对其临床诊治进行讨论。结果患者初次手术行右侧精索区脂肪组织送检。术后病检提示:高分化脂肪肉瘤。随访1年内,因复发分别行双侧睾丸根治性切除术及腹膜后肿瘤切除术。结论精索脂肪肉瘤是极为罕见的疾病,目前尚缺乏标准的治疗方案,局限性病变完整手术切除是关键,局部复发手术治疗仍是首选,无法达到R0切除,术后复发率极高,脂肪肉瘤对放疗和化疗不敏感,仍期待更确切的辅助疗法联合应用于该疾病的治疗。

Objective To explore the clinical features,diagnosis and treatment of liposarcoma of spermatic cord.Methods The clinical data of 1 case with multiple recurrence of liposarcoma of spermatic cord were retrospectively analyzed,and the clinical diagnosis and treatment were discussed in combination with relevant literature.Results The patient underwent the first operation to examine the adipocytes in the right spermatic cord area.Postoperative examination revealed highly differentiated liposarcoma.Within 1 year of follow-up,radical resection of both testis and retroperitoneal tumor were performed respectively due to recurrence.Conclusion liposarcoma of spermatic cord is an extremely rare disease,and currently there is no standard treatment protocol.Radical surgical resection of localized lesions is the key,and surgical treatment is still the first choice for local recurrence.As it is unable to achieve R0 resection,the recurrence rate is very high.Since liposarcoma is not sensitive to radiotherapy and chemotherapy,more precise adjuvant therapy is highly expected.