不同基质中大麻素类成分分析方法研究进展

Research Progress on Analytical Methods of Cannabinoids in Different Substrates

大麻素是大麻植物中特有的一类化合物,具有多种生物活性,已被广泛应用于药品、食品、化妆品及纺织品等行业。但是,大麻含有成瘾性成分Δ9-四氢大麻酚,这使得大麻的应用受到法律约束。为了防止大麻相关产品的滥用,保证产品的安全性和有效性,建立便捷、高效、环保、价廉的能适用于各种基质中大麻素类成分的分析方法显得尤为重要。然而,由于大麻素类成分较高的结构相似性、较差的稳定性及在基质中产生的基质效应,使分析工作异常复杂。目前关于大麻素类成分的质量控制尚未有统一的标准,而且分析方法复杂多样。基于以上问题,本文介绍了大麻素类成分的分类,阐述了大麻植株、生物样品、食品、化妆品和纺织品中大麻素的分析方法,展望了大麻素类成分分析方法今后的发展方向,以期为大麻的进一步开发及合理化应用提供有益帮助。

Cannabinoid is a kind of special compound in Cannabis sativa L.,with a variety of biological activities,which have been widely used in medicine,food,cosmetics,textile,and other industries.However,Cannabis sativa contains the addictive ingredientΔ9-tetrahydrocannabinol,which also makes the application of Cannabis sativa subject to legal constraints.To prevent the abuse of Cannabis sativa related products and ensure the safety and effectiveness of products,it is very important to establish convenient,efficient,environmentally friendly,and inexpensive analytical methods that can be applied to the cannabinoid components in various matrices.Because of the high structural similarity,the poor stability of cannabinoid structure and the matrix effect in different matrices,the analysis becomes more complicated.At present,there is no unified standard for the quality control of cannabinoids,and there are various analytical methods.Based on the above questions,this paper introduces the classification of cannabinoids,expounds on the analysis methods of cannabinoids in Cannabis sativa plants,biological samples,food,cosmetics,and textiles,and looks forward to the future development direction of cannabinoid analysis methods,to provide useful help for the further development and rational application of Cannabis sativa.