再次Bentall手术应用于主动脉根部病变的病例系列报道

Redo-Bentall surgery for aortic root lesions:a report of case series

目的观察再次升主动脉带瓣管道置换(Redo-Bentall)手术在主动脉根部病变中应用的临床效果。方法总结2010年6月至2022年4月我科接受再次Bentall手术的主动脉根部病变患者46例,其中男性35例,女性11例,年龄(43.37±12.79)岁,距上一次手术(4.96±6.76)年,收集、分析患者围手术期、随访期间临床资料,Kaplan-meier生存分析比较各病因组生存率。结果本组病例中心内膜炎9例、白塞氏病12例,其余病因25例。术后出现心跳骤停4例(8.70%)、肾功能衰竭4例(8.70%)、消化道出血2例(4.35%)、新发三度房室传导阻滞并安置永久起搏器2例(4.35%),围手术期死亡3例(6.52%)。出院后随访(5.03±3.27)年,失访5例(11.63%),死亡1例(2.33%),发生腔隙性脑梗死1例(2.33%),其余无严重出血或栓塞并发症。心内膜炎组(62.3%)、白塞氏病组(70.0%)远期生存率明显低于其余病因组(80.0%),差异具有统计学意义(P<0.05)。结论再次Bentall手术在主动脉根部病变中的应用是安全有效的,其中感染性心内膜炎、白塞氏病的患者生存率相对较低。

Objective To observe the clinical efficacy of Redo-Bentall surgery in the reoperation of aortic root lesions.Methods A retrospective analysis was performed on 46 patients who underwent Redo-Bentall surgery for aortic root lesions in our department from June 2010 to April 2022.They were 35 males and 11 females,at a mean age of 43.37±12.79 years,in 4.96±6.76 years since the last operation.General clinical data in perioperative period and during follow-up were collected and analyzed.Kaplan-Meier survival analysis was used to compare the survival rates of each etiological group.Results There were 9 cases of central end otitis,12 cases of Behset’s disease,and 25 cases of other causes.After operation,4 cases(8.70%)experienced cardiac arrest,4 cases(8.70%)renal failure,2 cases(4.35%)gastrointestinal bleeding,2 cases(4.35%)new third-degree atrioventricular block and 2 cases(4.35%)permanent pacemaker placement.In perioperative period,3 cases(6.52%)died in hospital.During a mean follow-up of 5.03±3.27 years after discharge,5 cases(11.63%)were lost to follow-up,1 case died(2.33%),1 case had lacunar infarction(2.33%),and no severe bleeding or embolism complications was observed in the rest patients.The long-term survival rate was significantly lower in the endocarditis group(62.3%)and the Behcet’s disease group(70%)than the other etiological groups(80%,P<0.05).Conclusion The application of Redo-Bentall in the reoperation of aortic root lesions is safe and effective,but the survival rate is quite lower in the patients with infective endocarditis and Behcet’s disease.