植物伤害信号分子细胞外DNA的研究进展

Research Progress of Plant Damage Signal Molecule—Extracellular DNA

在病原菌形成病变之前,植物的先天免疫系统可通过受体识别来源于病原菌的激发子或自身的内源伤害信号分子(damage-associated molecular patterns,DAMPs),并做出一系列的防御反应,从而阻断或降低病原菌的侵染。近年来的研究发现,植物细胞外自身DNA片段(esDNA)作为一种DAMP,对同种植株的生长产生了抑制作用,并触发了植株自身特异性的免疫响应。本文系统地总结了esDNA的产生、作用特点、信号途径、潜在受体以及应用等方面的研究进展,以期为esDNA进一步的理论研究与农业生产应用提供参考。

The innate immune system of plants plays an important role in disease defense.Under pathogen attack,plant innate immune system can perceive injury via recognition pathogen-derived elicitors and endogenous danger signals molecules(DAMPs)and activate various defense responses.This thereby blocks or reduces the invasion of pathogen.Recently,some studies found that plant extracellular self-DNA(esDNA)fragments as a DAMP induces plant growth inhibition and immune response.In this paper,the production,functional characteristics,signaling pathways,potential receptors,and applications of esDNA are systematically summarized,which provides good reference for the further basic study and agricultural application of the signal molecule.