消除乙型肝炎进展

Progress towards elimination of hepatitis B

本文综述了全球和中国消除乙型肝炎的新进展。虽然全球乙型肝炎疾病负担正在下降,但各国消除乙型肝炎的进展差异较大,在疾病负担最严重的20个国家中,孟加拉国、印度、印度尼西亚、日本和俄罗斯取得显著进展。中国继续保持新生儿乙型肝炎疫苗高覆盖率,首剂及时接种率为95.6%,3剂接种率为99.6%。从2016年到2022年,中国慢性乙型肝炎患者的诊断率由19%升至24%,治疗率由11%升至15%,但与世界卫生组织提出的2023年目标仍有较大距离。全球和中国仍需继续努力,砥砺奋进,加速实现2030年消除病毒性肝炎的宏伟目标。

This paper summarizes the latest progress in the elimination of hepatitis B worldwide and in China.Although the global burden of hepatitis B is decreasing,there is a large difference in the progress towards elimination across different countries,and among the 20 countries with the heaviest disease burden,Bangladesh,India,Indonesia,Japan,and Russia have achieved substantial progress.China continues to maintain a high HBV vaccination coverage for neonates,with an inoculation rate of 95.6%for timely birth dose and 99.6%for 3 doses.From 2016 to 2022,the diagnosis rate of patients with chronic hepatitis B in China have increased from 19%to 24%,and treatment rate have increased from 11%to 15%;however,there is still a big gap compared with the WHO targets by 2030.Further efforts are needed to eliminate viral hepatitis by 2030 globally and in China.