还原氨化法合成乙二胺研究进展

Research progress on synthesis of ethylenediamine by reductive amination

乙二胺是一类重要的化工原料和精细化工中间体,在医药、农药、材料、电镀工业、石化和助剂等领域广泛应用,发展乙二胺合成技术具有市场应用价值。在乙二胺合成策略中,醇的还原氨化法是最直接和最具有原子经济性的路线,可满足绿色可持续化工的发展。综述了近年来还原氨化法合成乙二胺的研究进展,按不同的乙二胺合成方法介绍了金属催化剂的研究进展及反应机理,并对还原氨化法合成乙二胺的研究趋势进行了展望。

Ethylenediamine is an essential chemical raw material and fine chemical intermediate,which is widely used in medicine,pesticides,materials,electroplating industry,petrochemical and auxiliary fields.The development of ethylenediamine synthesis technology has great application value in the market.Among the synthesis strategies of ethylenediamine,the reductive amination of alcohol is the most direct and atomically economical route,which can meet the development of green and sustainable chemical engineering.The paper summarized the research progress in the synthesis of ethylenediamine by reductive amination in recent years,introducing the advances on metal catalysts and mechanism study categorized by different synthetic methods of ethylenediamine.The research trend of the synthesis of ethylenediamine by reductive amination was also prospected.