高血压与相关眼部疾病的研究进展

Research Progress of Hypertension and Common Ocular Diseases

高血压是我国最常见的慢性疾病,是多种眼部疾病的突出危险因素。研究表明,高血压在缺血性视神经病变、青光眼、白内障等多种眼病的发生、发展和转归中扮演重要角色;高血压后视网膜血流灌注减少、微循环障碍、氧化应激和炎症反应、内皮损伤和新生血管形成是相关眼部疾病发生的共同病理改变。目前我国高血压患病率逐年上升,由其引发的眼部疾病也日益增加,本文就高血压与几种相关眼病关系进行综述,以期为高血压相关眼病在临床中的预防和治疗提供思路。

Hypertension is the most common chronic disease in China,and it’s a prominent risk factor for many ocular diseases.Studies have shown that hypertension plays an important role in the occurrence,development and outcome of many ocular diseases,such as ischemic optic neuropathy,glaucoma and cataract.Decreased retinal blood perfusion,microcirculation disturbance,oxidative stress and inflammation,endothelial injury and neovascularization are common pathological changes in the occurrence of related ocular diseases after hypertension.At present,the prevalence of hypertension in China is increasing year by year,and the eye diseases caused by it are also increasing.Therefore,this article reviews the relationship between hypertension and several related ocular diseases,in order to provide ideas for the prevention and treatment of hypertension related ocular diseases in clinic.