某院静配中心儿童静脉输液不合理处方分析

Analysis of Irrational Prescription of Intravenous Infusion for Children in Pharmacy Intravenous Admixture Services in a Hospital

目的 对我院静脉用药调配中心审核干预的处方进行统计分析,为儿科合理使用静脉药品提供参考依据。方法 调取静脉配置中心2022年4月至2023年4月189637份儿童静脉输液处方进行审核,对有干预或反馈记录的不合理用药处方进行分析。结果 汇总发现儿童静脉输液不合理处方810份,约占所有静脉输液处方的0.427%。不合理处方类型主要包括用法用量不适宜、溶媒选用不适宜、药物配制浓度不适宜、药物配伍禁忌和超说明书用药,构成比分别为36.5%、23.8%、18.0%、12.1%和6.5%;各临床科室不合理处方排名前三名分别是PICU、CICU及血液肿瘤科,占比依次为24.1%、18.0%和16.8%。结论 目前我院儿童静脉输液仍存在不合理处方,审方药师应及时发现并进行干预,确保儿童静脉输液安全、合理。

OBJECTIVE To anlalyze the irrational prescriptions of intravenous infusion for children,and to provide a reference basis for the rational use of intravenous drugs by pediatrics.METHODS 189637 pediatric intravenous infusion prescriptions prescribed from April 2022 to April 2023 were reviewed,and the irrational prescriptions with intervention or feedback records were analyzed.RESULTS A total of 810 unreasonable prescriptions for intravenous infusion in children were found,accounting for about 0.427% of all intravenous infusion prescriptions.The types of unreasonable prescriptions mainly included inappropriate dosage,inappropriate solvent,inappropriate concentration of drug,contraindications to drug compatibility and off-label use,with composition ratios of 36.5%,23.8%,18.0%,12.1% and 6.5%,respectively.From the incidence rate of unreasonable prescription in clinical department,the top three clinical department were PICU,CICU and hemato-oncology department,accounting for 24.1%,18.0% and 16.8%,respectively.CONCLUSION At present,there are still unreasonable prescription for intravenous infusion of children in our hospital,and the pharmacist should detect and intervene in time to ensure the safety and reasonableness of intravenous infusion for children.