子宫内膜异位症药物治疗研究进展

Advances of drug therapy for endometriosis

子宫内膜异位症是一种常见的雌激素依赖性疾病,是育龄期女性痛经和不孕的主要原因之一。激素治疗和手术治疗均为首选治疗方法,但长期使用激素类药物会影响生育能力,而手术干预复发率高,且影响卵巢储备功能。因此,对现有治疗方案的完善及探索新的治疗药物是非常有意义的。本文主要讨论EM的药物治疗方法,以期为EM的治疗提供新思路。

Endometriosis of the women of reproductive age is a frequent estrogen-dependent disease,serving as a leading cause of dysmenorrhea or infertility of the women.The first-line treatment approaches of the endometriosis encompass hormonal and surgical interventions.Nevertheless,the prolonged administration of hormonal medications of the women with endometriosis may adversely impact their fertility.While the surgical intervention of the women exhibits the high recurrence rate of their endometriosis and may reduce their ovarian reserve.Therefore,improving the existing treatment strategies and exploring the new therapeutic drugs for the women with endometriosis are of significant importance.This paper elaborates on the pharmacological methods for treating the women with endometriosis,aiming to provide the new idea for treating the endometriosis.