Coexistent ankylosing spondylitis and intellectual developmental disorder with behavioral abnormalities and craniofacial dysmorphism with or without seizures

To the Editor,Ankylosing spondylitis(AS)is a chronic inflammatory rheumatic disease mainly affecting the axial skeleton,with chronic back pain and spinal stiffness as primary presenting symptoms.1 AS is heritable and exhibits familial aggregation.2 The disease course is frequently complicated with other immune diseases,cardiovascular disease,and depression3.