严重产后出血时母体血流动力学变化和组织病理生理改变

Changes in maternal hemodynamics and tissue pathophysiology during severe postpartum hemorrhage

妊娠期和产褥期母体血容量会发生生理性变化,在此基础上严重产后出血时母体会发生显著血流动力学变化和组织病理生理改变,导致孕产妇失血性休克、弥散性血管内凝血及多器官功能损伤甚至衰竭。了解这些病理过程有助于临床早期识别和正确救治方案的实施,降低孕产妇死亡率。

Maternal blood volume changes during pregnancy and puerperium.Severe postpartum hemorrhage leads to significant hemodynamic and histopathological changes,which may result in hemorrhagic shock,disseminated intravascular coagulation,and multiple organ dysfunction or failure.Understanding these pathological processes is helpful for early clinical recognition and correct treatment,which reduces maternal mortality.