摘要
HIV耐药毒株的流行影响了抗逆转录病毒治疗(ART)效果,降低了HIV感染者体内病毒抑制率并导致HIV的二代传播。HIV感染者尚不能治愈,需要终身服药。一旦由于某种原因导致治疗失败,可能会出现HIV耐药毒株,导致HIV耐药在我国未治疗人群中产生并传播。本文就我国治疗前HIV耐药毒株流行的研究进展进行了文献综述。
The prevalence of HIV resistant strains has affected the effectiveness of antiretroviral therapy,reducing the viral inhibition rate in HIV-infected individuals and leading to second-generation transmission of HIV.HIV infected individuals cannot be cured yet and require lifelong medication.Once treatment fails due to various reasons,drug-resistant strains of HIV may emerge,which may lead to the emergence and spread of HIV resistance among the untreated population in Chi-na.This article provides a literature review on research progress of pretreatment HIV resistant strains in China.
作者
陈宏利
李丹
冯毅
阮玉华
CHEN Hongli;LI Dan;FENG Yi;RUAN Yuhua(State Key Laboratory of Infectious Disease Control and Prevention,National Center for AIDS/STD Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China)
出处
《安徽预防医学杂志》
2024年第1期34-38,共5页
Anhui Journal of Preventive Medicine
基金
国家科技部十四五重大专项(2022YFC2305205)
国家自然科学基金(82260670)
广西艾滋病防控与成果转化研究重点实验室(ZZH2020010)
广西八桂学者艾滋病防控关键技术岗位专项
广西医疗卫生重点学科建设项目。
