摘要
目的比较分析1990年与2019年中国、美国和德国良性前列腺增生(benign prostatic hyperplasia,BPH)的疾病负担。方法利用2019年发布的全球疾病负担数据库(Global Burden of Disease 2019,GBD 2019),对比研究1990年与2019年的中国、美国、德国BPH患病率、发病率、伤残损失寿命年(years lived with disability,YLD)及其标化率。结果与1990年相比,2019年中国、美国和德国患病例数、发病例数及YLD均升高。2019年中国各年龄段BPH患病率、发病率和YLD率总体上均随年龄增加而升高,75~79岁年龄段BPH发病率最高。2019年美国BPH患病率和YLD率随年龄增加而升高,在≥80岁年龄组老年人中最高,而BPH发病率在70~74岁年龄段最高。1990年与2019年,德国65~69岁年龄段BPH发病率最高,75~79岁年龄段患病率最高,75~79岁年龄组YLD率最高。1990—2019年,三国YLD均呈上升趋势,2019年中国、美国、德国BPH的YLD分别为40.62万人年、8.94万人年、2.73万人年。结论中国、美国、德国BPH疾病负担较大,其中我国BPH疾病负担高于美国和德国,尤其是65岁以上和农村偏远地区人群,未来应主动对BPH高危人群进行健康指导,并且给予更多医疗资源倾斜。
Objective To comparatively analyze the disease burden of benign prostatic hyperplasia(BPH)in China,the United States,and Germany between 1990 and 2019.Methods The Global Burden of Disease 2019(GBD 2019)was used to comparatively study the prevalence,incidence,years lived with disability(YLD),and standardized rate in China,the United States and Germany between 1990 and 2019.Results Compared with 1990,the number of prevalence cases,incidence cases and YLD in China,the United States and Germany all showed an increasing trend in 2019.The prevalence,incidence and YLD rate of BPH patients of all ages in China continued to increase with age,with the highest BPH incidence occuring in the age group of 75~79 years old.In 2019,the prevalence of BPH and YLD rate in the United States increased with age,and were the highest among the elderly aged 80 and above,while the incidence of BPH was the highest in the age group of 70~74 years old.In 1990 and 2019,the incidence of BPH among people aged from 65 to 69 in Germany was the highest,and the age group with the highest prevalence was 75 to 79 years old.BHP patients in 75-79 age group has the highest YLD in Germany.From 1990 to 2019,YLD showed an increasing trend in all three countries.In 2019,the YLD of BPH in China,the United States and Germany was 406,200,89,400 and 27,300 person-years respectively.Conclusion China,the United States,and Germany bear a heavy disease burden of BPH,with China having a higher BPH disease burden than the United States and Germany,particularly among those over 65 years of age and populations in rural and remote areas.Proactive health guidance should be provided for highrisk groups in the future,along with a greater allocation of medical resources.
作者
陆沛文
訾豪
钱信行
明道靖
方程
李晓东
LU Peiwen;ZI Hao;QIAN Xinhang;MING Daojing;FANG Cheng;LI Xiaodong(Department of Urology,Huaihe Hospital of Henan University,Kaifeng 475000,Henan Province,China;Center for Evidence-Based and Translational Medicine,Zhongnan Hospital of Wuhan University,Wuhan 430071,China;Department of Urology,The First Affiliated Hospital of Henan University,Kaifeng 475000,Henan Province,China)
出处
《医学新知》
CAS
2024年第5期545-553,共9页
New Medicine
基金
国家自然科学基金青年科学基金项目(82200862)
湖北省自然科学基金青年项目(2022CFB681)。
关键词
良性前列腺增生
疾病负担
发病率
患病率
伤残损失寿命年
Benign prostatic hyperplasia
Disease burden
Prevalence rate
Incidence rate
Years lived with disability