肝癌经导管动脉化疗栓塞术后胃肠道反应管理的证据总结

Summary of the evidences for the management of gastrointestinal reactions after TACE of hepatocellular carcinoma

目的总结肝癌经导管动脉化疗栓塞术(TACE)后胃肠道反应管理的最佳证据,为临床护理决策提供参考。方法根据“6S”循证护理模型,检索PubMed、Web of Science、The Cochrane Library、Embase、CINAHL、JBI循证、UpToDate、BMJ Best Practice、SinoMed、万方、知网、梅斯医学、医脉通、美国临床肿瘤学会(ASCO)、美国肿瘤护理学会(ONS)、美国国立综合癌症网络(NCCN)、多国癌症支持治疗学会/欧洲肿瘤内科学会(MASCC/ESMO)、日本癌症治疗学会(JSCO)等数据库,时限自建库至2023年3月30日。评价纳入文献质量并提取证据。结果共纳入12篇文献。最终从护理方式、护理观察、药物治疗、中医护理、饮食护理、对症护理以及其他等7个维度总结形成18条最佳证据。结论提炼出肝癌TACE术后胃肠道反应管理最佳证据,为临床医护人员护理TACE介入治疗后患者提供参考。

Objective To summarize the best evidences for managing gastrointestinal reactions after TACE therapy of liver cancer,so as to provide reference for making clinical nursing decisions.Methods Based on the“6S”evidence-based nursing mode,a computerized retrieval of academic papers concerning the evidence of managing gastrointestinal reactions after TACE from the databases of PubMed,Web of Science,Cochrane Library,Embase,CINAHL,JBI evidence-based database,UpToDate,BMJ Best Practice,SinoMed,Wanfang Database,CNKI,Meis Medical,Yimaitong,ASCO,ONS,NCCN,MASCC/ESMO,and JSCO was conducted.The retrieval time period was from the establishment of the database to March 30,2022.The quality of the included literature was evaluated,and the evidences were extracted.Results A total of 12 articles were enrolled in this study.Finally,18 best evidences were summarized from the following seven dimensions:nursing mode,nursing observation,drug therapy,traditional Chinese medicine nursing,dietary nursing,symptomatic nursing,and other aspects.Conclusion The best evidences for the management of gastrointestinal reactions after TACE therapy of liver cancer are extracted,which provide a useful reference for clinical medical staff in nursing patients with liver cancer after receiving TACE.