中医辨证施治治疗脾胃虚寒型慢性胃炎的临床效果分析

Clinical effect analysis of dialectical treatment of chronic gastritis of deficiency cold of spleen and stomach type in traditional Chinese medicine

目的探讨中医辨证施治治疗脾胃虚寒型慢性胃炎的临床效果分析。方法64例脾胃虚寒型慢性胃炎患者,随机分为对照组和观察组,每组32例。对照组使用常规西医治疗,观察组在此基础上使用中医辨证施治。比较两组的临床疗效及治疗前后中医证候积分、血清炎性因子[白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)]。结果观察组治疗总有效率为93.75%,明显高于对照组的68.75%(P<0.05)。治疗后,观察组胃脘隐痛、喜温喜按、泛吐清水、便溏、神疲乏力积分分别为(0.90±0.18)、(0.87±0.16)、(0.92±0.19)、(0.86±0.17)、(0.93±0.20)分,均低于对照组的(1.47±0.23)、(1.44±0.22)、(1.50±0.24)、(1.46±0.23)、(1.51±0.24)分(P<0.05)。治疗后,观察组IL-1β、IL-6、TNF-α、CRP水平分别为(14.27±2.54)ng/L、(20.33±3.02)ng/L、(4.59±0.78)ng/L、(3.02±0.75)mg/L,低于对照组的(18.96±3.31)ng/L、(27.84±3.56)ng/L、(7.13±1.16)ng/L、(6.87±1.28)mg/L(P<0.05)。结论中医辨证施治治疗脾胃虚寒型慢性胃炎的临床效果显著,能有效缓解中医证候,减轻炎症反应,具有积极的临床意义。

Objective To explore the clinical effect of dialectical treatment of chronic gastritis of deficiency cold of spleen and stomach type in traditional Chinese medicine.Methods 64 patients with chronic gastritis of deficiency cold of spleen and stomach type were randomly divided into a control group and an observation group,with 32 cases in each group.The control group was treated with conventional western medicine,and the observation group was treated with dialectical treatment of traditional Chinese medicine.The clinical efficacy,traditional Chinese medicine syndrome score,serum inflammatory factors[interleukin-1β(IL-1β),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),C-reactive protein(CRP)]of the two groups were compared.Results The total effective rate of the observation group was 93.75%,which was significantly higher than the control group's 68.75%(P<0.05).After treatment,the scores of epigastric dull pain,predilection for warmth and pressure,spit clear water,loose stool and fatigue in the observation group were(0.90±0.18),(0.87±0.16),(0.92±0.19),(0.86±0.17)and(0.93±0.20)points,which were lower than(1.47±0.23),(1.44±0.22),(1.50±0.24),(1.46±0.23)and(1.51±0.24)points in the control group(P<0.05).After treatment,the levels of IL-1β,IL-6,TNF-α and CRP in the observation group were(14.27±2.54)ng/L,(20.33±3.02)ng/L,(4.59±0.78)ng/L and(3.02±0.75)mg/L,which were lower than(18.96±3.31)ng/L,(27.84±3.56)ng/L,(7.13±1.16)ng/L and(6.87±1.28)mg/L in the control group(P<0.05).Conclusion The clinical effect of dialectical treatment of chronic gastritis of deficiency cold of spleen and stomach type in traditional Chinese medicine is remarkable,which can effectively relieve the traditional Chinese medicine syndromes and reduce inflammatory reaction,and has positive clinical significance.