157例精神科住院患者药物使用情况调查分析

Investigation and Analysis of Drug Use in 157 Psychiatric Inpatients

目的:分析某院精神科住院患者的用药情况,以期提高精神科合理用药水平。方法:选取2022年12月28日某院精神科157例住院患者的用药资料进行统计分析,总结患者的基本情况、精神药物的使用频率和日使用剂量情况、辅助用药情况以及精神药物治疗方案。结果:157例患者中精神分裂症患者最多(78.34%),男性比例(82.17%)大于女性(17.83%),且44~59岁的中年患者居多(48.41%);非典型抗精神病药物的使用最多,其中喹硫平的使用比例最高(56.69%);单用一种抗精神病药的患者共89例(56.69%),两种以上抗精神病药联用的患者共68例(43.31%),以奥氮平与喹硫平联用最常见;抗精神病药与其他精神药物联用的患者共68例(43.31%),其中联用镇静催眠药和心境稳定剂最多。辅助用药中解热镇痛类和心血管类药物使用最多。精神药物的日使用剂量均在规定范围内。结论:某院精神药物的使用基本合理,抗精神病药的联用情况较多,临床医师应规范联合用药,临床药师应及时进行药学评估和药学监护,加强药物不良反应的防治。

Objective:To analyze the drug use of inpatients in psychiatric department in our hospital and to improve the level of rational drug use in psychiatric department.Methods:The medication data of 157 inpatients in the psychiatric department of our hospital on December 28,2022 were statistically analyzed,and the basic situation of the patients,the frequency and daily dose of psychotropic drugs,the auxiliary drugs and the treatment plan of psychotropic drugs were summarized.Results:Among the 157 patients,schizophrenia was the most common(78.34%),the proportion of male(82.17%)was higher than that of female(17.83%),and most of the middle-aged patients between 44 and 59 years old(48.41%).Atypical antipsychotics were used most frequently,of which quetiapine was the highest(56.69%),89 patients(56.69%)were treated with one antipsychotic alone,68 patients(43.31%)were treated with more than two antipsychotics,and olanzapine combined with quetiapine was the most common,and 68 patients(43.31%)were treated with antipsychotics combined with other psychotropic drugs,of which the most were sedative hypnotics and mood stabilizers.Antipyretic,analgesic and cardiovascular drugs are the most commonly used in adjuvant drugs.The daily dose of psychotropic drugs is within the prescribed range.Conclusion:The use of psychotropic drugs in our hospital is basically reasonable,and there are many cases of combined use of antipsychotic drugs.Clinicians should standardize the combined use of antipsychotic drugs,clinical pharmacists should carry out pharmaceutical evaluation and pharmaceutical care in time,and strengthen the prevention and treatment of adverse drug reactions.