成人甲型肝炎疫苗接种专家建议

Expert recommendations on hepatitis A vaccination for adults

甲型肝炎(简称甲肝)是全球严重的公共卫生问题之一,成人甲肝临床症状重,可进展为急性肝衰竭。随着以甲肝疫苗接种为基础的综合性防控措施的实施,中国报告的儿童甲肝发病率明显下降,成人成为甲肝主要发病人群,导致成人甲肝疾病负担逐渐显现。成人接种甲肝疫苗是预防甲肝的重要措施。《成人甲型肝炎疫苗接种专家建议》根据世界卫生组织(World Health Organization,WHO)关于甲肝疫苗的立场文件(2022年),综合国内外最新研究进展和国内专家意见编撰而成,旨在提出中国成人甲肝疫苗接种建议,为公共卫生和预防接种专业人员在科学使用甲肝疫苗及其最佳免疫效果提供证据,提高甲肝的防控水平。

Hepatitis A is a significant global public health concern,with severe clinical symptoms in adult cases that can progress to acute hepatic failure.With the implementation of comprehensive prevention and control measures based on vaccination,the reported incidence of hepatitis A in children has notably decreased in China,while the incidence of hepatitis A in adults has gradually increased.Vaccination against hepatitis A in adults remains a crucial preventive measure.This recommendation is formulated based on the World Health Organization's position paper on hepatitis A vaccines(2022),incorporating the latest domestic and international research advancements and opinions from domestic experts.Its aim is to provide recommendations for hepatitis A vaccination among Chinese adults,offering evidence for public health and vaccination professionals to scientifically use hepatitis A vaccines and maximize their preventive efficacy,thereby enhancing hepatitis A prevention and control efforts.