四妙散治疗急性痛风性关节炎的药理、临床及实验研究进展

Progress in Pharmacology,Clinical and Experimental Research on the Treatment of Acute Gouty Arthritis with Simiao Powder

痛风性关节炎是多系统受累的全身性疾病,具有高发病率、高复发率、年轻化趋势的特点,严重者可造成关节畸形、骨质破坏,探讨痛风性关节炎的治疗对人类健康具有重要意义。四妙散是临床上治疗痛风性关节炎的经典方剂,具有很好的临床效果;四妙散治疗急性痛风性关节炎(AGA)具有多靶点、多通路协同作用,安全性高等特点,在缓解炎症、改善临床症状、改善实验室指标以及降低不良反应发生率和复发率等方面具有良好的效果,临床上值得推荐使用,尤其是有西药使用禁忌证时。

Gouty arthritis is a systemic disease that affects multiple systems,characterized by high incidence rate,high recurrence rate,and a trend towards affecting younger individuals.Severe cases can cause joint deformities and bone destruction.It is of great significance to explore the treatment of gouty arthritis for human health.Simiao Powder is a classic formula for treating gouty arthritis in clinical practice,with good clinical effects.Simiao Powder treats acute gouty arthritis(AGA)through multiple targets,multiple pathways,offering high safety.It has good effects in alleviating inflammation,improving clinical symptoms,improving laboratory indicators,and reducing the incidence of adverse reactions and recurrence rates.It is recommended for clinical use,especially when there are contraindications to Western medicine use.