复方黄柏液涂剂联合一次性切开挂线根治术在肛周脓肿患者中的应用

Application of Compound Huangbai Liquid Coating combined with one-time incision and lateral thread radical resection in patients with perianal abscess

目的 观察复方黄柏液涂剂联合一次性切开挂线根治术(OITHRS)在肛周脓肿(PA)中应用的效果。方法 将我院132例PA患者随机分为治疗组与对照组各66例。对照组采用OITHRS治疗,治疗组采用复方黄柏液涂剂辅助OITHRS治疗。对比两组总有效率,比较术后第1天、第25天肛周分泌物、肉芽形态、组织水肿、创面疼痛评分;比较术前、术后第25天Wexner评分、肛管静息压、肛管最大收缩压;比较两组腐肉脱落时间、愈合时间及创面感染、脓肿复发、肛门功能障碍发生情况。结果 治疗后,治疗组总有效率高于对照组(P<0.05);术后第25天,两组症状低于术后第1天,治疗组症状评分低于对照组(P<0.05);术后第25天,两组Wexner评分、肛管静息压、肛管最大收缩压低于术前,治疗组Wexner评分低于对照组,肛管静息压、肛管最大收缩压高于对照组(P<0.05);治疗组腐肉脱落时间、愈合时间短于对照组(P<0.05);治疗组创面感染、脓肿复发、肛门功能障碍发生情况低于对照组(P<0.05)。结论 复方黄柏液涂剂联合OITHRS在PA患者中应用效果较好,促进切口愈合,提高肛门功能,减少感染、复发等不良反应的发生。

Objective To observe the effect of Compound Huangbai Liquid Coating combined with one-time incision and lateral thread resection(OITHRS)in perianal abscess(PA).Methods A total of 132 patients with PA were randomly divided into treatment group and control group,66 cases each.Control group was treated with OITHRS,while treatment group was treated with Compound Huangbai Liquid Coating on the basis of control group.The total effective rate,the scores of perianal discharge,granulation morphology,tissue edema,and wound pain on the 1st and 25th days after surgery,the preoperative and postoperative 25-day Wexner score,anal canal resting pressure,and anal canal maximum systolic blood pressure,the sloughing time,healing time,wound infection,abscess recurrence and incidence of anal dysfunction were compared between the two groups.Results After treatment,the total effective rate of treatment group was higher than control group(P<0.05);the symptoms of both groups on the 25th day after surgery were lower than those on the lst day after operation,which were lower in treatment group than control group(P<0.05);the Wexner score was lower in treatment group than control group,anal canal resting pressure and maximum anal systolic blood pressure in both groups were lower than those before operation and on the 25th day after operation,which were higher than control group(P<0.05);the healing time of treatment group was shorter than that of control group(P<0.05);the incidence of wound infection,abscess recurrence and anal dysfunction in treatment group was lower than control group(P<0.05).Conclusion The application effect of Compound Huangbai Liquid Coating combined with OITHRS in patients with PA is good,which canpromote incision healing,improve anal function,and reduce the occurrence of adverse reactions such as infection and recurrence.